Keck M - Search Results

1

Orally Active Aminopeptidase A Inhibitor Prodrugs: Current State and Future Directions.

Keck M, Hmazzou R, Llorens-Cortes C. Keck M, et al. Curr Hypertens Rep. 2019 May 21;21(7):50. doi: 10.1007/s11906-019-0957-4. Curr Hypertens Rep. 2019. PMID: 31115779 Review.

2

Brain renin-angiotensin system blockade with orally active aminopeptidase A inhibitor prevents cardiac dysfunction after myocardial infarction in mice.

Boitard SE, Marc Y, Keck M, Mougenot N, Agbulut O, Balavoine F, Llorens-Cortes C. Boitard SE, et al. Among authors: keck m. J Mol Cell Cardiol. 2019 Feb;127:215-222. doi: 10.1016/j.yjmcc.2018.12.008. Epub 2018 Dec 30. J Mol Cell Cardiol. 2019. PMID: 30599150

3

NI956/QGC006, a Potent Orally Active, Brain-Penetrating Aminopeptidase A Inhibitor for Treating Hypertension.

Keck M, De Almeida H, Compère D, Inguimbert N, Flahault A, Balavoine F, Roques B, Llorens-Cortes C. Keck M, et al. Hypertension. 2019 Jun;73(6):1300-1307. doi: 10.1161/HYPERTENSIONAHA.118.12499. Hypertension. 2019. PMID: 31067198

4

QGC606: A Best-in-Class Orally Active Centrally Acting Aminopeptidase A Inhibitor Prodrug for Treating Heart Failure Following Myocardial Infarction.

Boitard SE, Keck M, Deloux R, Girault-Sotias PE, Marc Y, De Mota N, Compere D, Agbulut O, Balavoine F, Llorens-Cortes C. Boitard SE, et al. Among authors: keck m. Can J Cardiol. 2022 Jun;38(6):815-827. doi: 10.1016/j.cjca.2022.01.019. Epub 2022 Jan 26. Can J Cardiol. 2022. PMID: 35091008 Free article.

5

A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia.

Flahault A, Girault-Sotias PE, Keck M, Alvear-Perez R, De Mota N, Estéoulle L, Ramanoudjame SM, Iturrioz X, Bonnet D, Llorens-Cortes C. Flahault A, et al. Among authors: keck m. Nat Commun. 2021 Jan 12;12(1):305. doi: 10.1038/s41467-020-20560-y. Nat Commun. 2021. PMID: 33436646 Free PMC article.

6

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism.

Flahault A, Keck M, Girault-Sotias PE, Esteoulle L, De Mota N, Bonnet D, Llorens-Cortes C. Flahault A, et al. Among authors: keck m. Front Pharmacol. 2021 Jul 26;12:715095. doi: 10.3389/fphar.2021.715095. eCollection 2021. Front Pharmacol. 2021. PMID: 34393794 Free PMC article.

7

Cardiac inflammatory CD11b/c cells exert a protective role in hypertrophied cardiomyocyte by promoting TNFR₂- and Orai3- dependent signaling.

Keck M, Flamant M, Mougenot N, Favier S, Atassi F, Barbier C, Nadaud S, Lompré AM, Hulot JS, Pavoine C. Keck M, et al. Sci Rep. 2019 Apr 15;9(1):6047. doi: 10.1038/s41598-019-42452-y. Sci Rep. 2019. PMID: 30988334 Free PMC article.

8

Early activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.

Flamant M, Mougenot N, Balse E, Le Fèvre L, Atassi F, Gautier EL, Le Goff W, Keck M, Nadaud S, Combadière C, Boissonnas A, Pavoine C. Flamant M, et al. Among authors: keck m. Sci Rep. 2021 Sep 9;11(1):17982. doi: 10.1038/s41598-021-97493-z. Sci Rep. 2021. PMID: 34504250 Free PMC article.

9

Emergence of Orai3 activity during cardiac hypertrophy.

Saliba Y, Keck M, Marchand A, Atassi F, Ouillé A, Cazorla O, Trebak M, Pavoine C, Lacampagne A, Hulot JS, Farès N, Fauconnier J, Lompré AM. Saliba Y, et al. Among authors: keck m. Cardiovasc Res. 2015 Mar 1;105(3):248-59. doi: 10.1093/cvr/cvu207. Epub 2014 Sep 11. Cardiovasc Res. 2015. PMID: 25213556 Free PMC article.

10

A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor.

Droctové L, Ciolek J, Mendre C, Chorfa A, Huerta P, Carvalho C, Gouin C, Lancien M, Stanajic-Petrovic G, Braco L, Blanchet G, Upert G, De Pauw G, Barbe P, Keck M, Mourier G, Mouillac B, Denis S, Rodríguez de la Vega RC, Quinton L, Gilles N. Droctové L, et al. Among authors: keck m. Br J Pharmacol. 2022 Jul;179(13):3470-3481. doi: 10.1111/bph.15814. Epub 2022 Feb 28. Br J Pharmacol. 2022. PMID: 35122240 Free article.

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