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Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.
Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G. Kirkman LA, et al. Among authors: kawasaki m. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6863-E6870. doi: 10.1073/pnas.1806109115. Epub 2018 Jul 2. Proc Natl Acad Sci U S A. 2018. PMID: 29967165 Free PMC article.
Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome.
Zhang H, Hsu HC, Kahne SC, Hara R, Zhan W, Jiang X, Burns-Huang K, Ouellette T, Imaeda T, Okamoto R, Kawasaki M, Michino M, Wong TT, Toita A, Yukawa T, Moraca F, Vendome J, Saha P, Sato K, Aso K, Ginn J, Meinke PT, Foley M, Nathan CF, Darwin KH, Li H, Lin G. Zhang H, et al. Among authors: kawasaki m. J Med Chem. 2021 May 13;64(9):6262-6272. doi: 10.1021/acs.jmedchem.1c00296. Epub 2021 May 5. J Med Chem. 2021. PMID: 33949190 Free PMC article.
Cyclic Sesquiterpene-Flavanone [4+2] Hybrids, Syzygioblanes A-C, Found in an Indonesian Traditional Medicine, "Jampu Salo" (Syzygium oblanceolatum).
Koga N, Saito Y, Miyake K, Amuti S, Fukuyoshi S, Yoshida S, Sato S, Yamada Y, Ikeda A, Adachi N, Kawasaki M, Takasu A, Aramaki S, Senda T, Rahim A, Najib A, Alam G, Tanaka N, Nakagawa-Goto K. Koga N, et al. Among authors: kawasaki m. Org Lett. 2024 May 10. doi: 10.1021/acs.orglett.4c01248. Online ahead of print. Org Lett. 2024. PMID: 38728049
Impact of Left Atrial Appendage Flow Velocity on Thrombus Resolution and Clinical Outcomes in Patients with Atrial Fibrillation and Silent Left Atrial Thrombi: Insights from the LAT Study.
Okada M, Inoue K, Tanaka N, Tanaka K, Hirao Y, Iwakura K, Egami Y, Masuda M, Watanabe T, Minamiguchi H, Oka T, Hikoso S, Sunaga A, Okada K, Nakatani D, Sotomi Y, Sakata Y; Osaka Cardiovascular Conference (OCVC)-Arrhythmia Investigators. Okada M, et al. Europace. 2024 May 1:euae120. doi: 10.1093/europace/euae120. Online ahead of print. Europace. 2024. PMID: 38691672
Clinical Outcomes and Return-to-Sport Rates following Fragment Fixation Using Hydroxyapatite/Poly-L-Lactate Acid Threaded Pins for Knee Osteochondritis Dissecans: A Case Series.
Shimizu T, Murata Y, Nakashima H, Nishimura H, Suzuki H, Kawasaki M, Tsukamoto M, Sakai A, Uchida S. Shimizu T, et al. Among authors: kawasaki m. Biomimetics (Basel). 2024 Apr 13;9(4):232. doi: 10.3390/biomimetics9040232. Biomimetics (Basel). 2024. PMID: 38667242 Free PMC article.
Long-Term Outcomes of Endovascular Aneurysm Repair in Patients Aged ≤70 Years.
Onohara T, Handa N, Kawasaki M, Kasashima F, Saito T, Nakamura T, Une D, Nakai M, Shiraya S, Maeda K, Imai K, Yamamoto T, Shimoe Y, Okamoto M, Kawazu Y; National Hospital Organization Network Study Group in Japan for Abdominal Aortic Aneurysm. Onohara T, et al. Among authors: kawasaki m. Ann Vasc Dis. 2024 Mar 25;17(1):25-33. doi: 10.3400/avd.oa.23-00072. Epub 2024 Feb 6. Ann Vasc Dis. 2024. PMID: 38628930 Free PMC article.
Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules.
Hamaguchi-Suzuki N, Adachi N, Moriya T, Yasuda S, Kawasaki M, Suzuki K, Ogasawara S, Anzai N, Senda T, Murata T. Hamaguchi-Suzuki N, et al. Among authors: kawasaki m. Biochem Biophys Res Commun. 2024 May 21;709:149855. doi: 10.1016/j.bbrc.2024.149855. Epub 2024 Mar 28. Biochem Biophys Res Commun. 2024. PMID: 38579618 Free article.
1,476 results