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Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Liu XT, Huang Y, Liu D, Jiang YC, Zhao M, Chung LH, Han XD, Zhao Y, Chen J, Coleman P, Ting KK, Tran C, Su Y, Dennis CV, Bhatnagar A, Liu K, Don AS, Vadas MA, Gorrell MD, Zhang S, Murray M, Kavurma MM, McCaughan GW, Gamble JR, Qi Y. Liu XT, et al. Among authors: kavurma mm. J Transl Med. 2024 Jan 10;22(1):43. doi: 10.1186/s12967-023-04830-z. J Transl Med. 2024. PMID: 38200582 Free PMC article.
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia-Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide-Dependent Mechanisms.
Di Bartolo BA, Cartland SP, Prado-Lourenco L, Griffith TS, Gentile C, Ravindran J, Azahri NS, Thai T, Yeung AW, Thomas SR, Kavurma MM. Di Bartolo BA, et al. Among authors: kavurma mm. J Am Heart Assoc. 2015 Nov 16;4(11):e002527. doi: 10.1161/JAHA.115.002527. J Am Heart Assoc. 2015. PMID: 26572549 Free PMC article.
On the TRAIL of obesity and diabetes.
Harith HH, Morris MJ, Kavurma MM. Harith HH, et al. Among authors: kavurma mm. Trends Endocrinol Metab. 2013 Nov;24(11):578-87. doi: 10.1016/j.tem.2013.07.001. Epub 2013 Aug 12. Trends Endocrinol Metab. 2013. PMID: 23948591 Review.
TRAIL signals, extracellular matrix and vessel remodelling.
Patil MS, Cartland SP, Kavurma MM. Patil MS, et al. Among authors: kavurma mm. Vasc Biol. 2020 Jun 15;2(1):R73-R84. doi: 10.1530/VB-20-0005. eCollection 2020. Vasc Biol. 2020. PMID: 32923976 Free PMC article. Review.
54 results