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Identification of Hsp90 Inhibitors with Anti-Plasmodium Activity.
Posfai D, Eubanks AL, Keim AI, Lu KY, Wang GZ, Hughes PF, Kato N, Haystead TA, Derbyshire ER. Posfai D, et al. Among authors: kato n. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01799-17. doi: 10.1128/AAC.01799-17. Print 2018 Apr. Antimicrob Agents Chemother. 2018. PMID: 29339390 Free PMC article.
Chemical interrogation of the malaria kinome.
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J. Derbyshire ER, et al. Among authors: kato n. Chembiochem. 2014 Sep 5;15(13):1920-30. doi: 10.1002/cbic.201400025. Epub 2014 Aug 8. Chembiochem. 2014. PMID: 25111632 Free PMC article.
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan GL, Duffy S, Eckley S, Itoe MA, Koolen KM, Lewis TA, Lui PS, Lukens AK, Lund E, March S, Meibalan E, Meier BC, McPhail JA, Mitasev B, Moss EL, Sayes M, Van Gessel Y, Wawer MJ, Yoshinaga T, Zeeman AM, Avery VM, Bhatia SN, Burke JE, Catteruccia F, Clardy JC, Clemons PA, Dechering KJ, Duvall JR, Foley MA, Gusovsky F, Kocken CH, Marti M, Morningstar ML, Munoz B, Neafsey DE, Sharma A, Winzeler EA, Wirth DF, Scherer CA, Schreiber SL. Kato N, et al. Nature. 2016 Oct 20;538(7625):344-349. doi: 10.1038/nature19804. Epub 2016 Sep 7. Nature. 2016. PMID: 27602946 Free PMC article.
High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.
Plouffe DM, Wree M, Du AY, Meister S, Li F, Patra K, Lubar A, Okitsu SL, Flannery EL, Kato N, Tanaseichuk O, Comer E, Zhou B, Kuhen K, Zhou Y, Leroy D, Schreiber SL, Scherer CA, Vinetz J, Winzeler EA. Plouffe DM, et al. Among authors: kato n. Cell Host Microbe. 2016 Jan 13;19(1):114-26. doi: 10.1016/j.chom.2015.12.001. Epub 2015 Dec 31. Cell Host Microbe. 2016. PMID: 26749441 Free PMC article.
Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents.
Huang J, Yuan Y, Zhao N, Pu D, Tang Q, Zhang S, Luo S, Yang X, Wang N, Xiao Y, Zhang T, Liu Z, Sakata-Kato T, Jiang X, Kato N, Yan N, Yin H. Huang J, et al. Among authors: kato n. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2017749118. doi: 10.1073/pnas.2017749118. Proc Natl Acad Sci U S A. 2021. PMID: 33402433 Free PMC article.
3,852 results