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Synthesis, conformational analysis and glycosidase inhibition of bicyclic nojirimycin C-glycosides based on an octahydrofuro[3,2-b]pyridine motif.
Désiré J, Foucart Q, Poveda A, Gourlaouen G, Shimadate Y, Kise M, Proceviat C, Ashmus R, Vocadlo DJ, Jiménez-Barbero J, Kato A, Blériot Y. Désiré J, et al. Among authors: kato a. Carbohydr Res. 2022 Jan;511:108491. doi: 10.1016/j.carres.2021.108491. Epub 2021 Dec 20. Carbohydr Res. 2022. PMID: 34953389 Free article.
C-branched iminosugars: α-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP compared to miglitol and miglustat.
Jenkinson SF, Best D, Saville AW, Mui J, Martínez RF, Nakagawa S, Kunimatsu T, Alonzi DS, Butters TD, Norez C, Becq F, Blériot Y, Wilson FX, Weymouth-Wilson AC, Kato A, Fleet GW. Jenkinson SF, et al. Among authors: kato a. J Org Chem. 2013 Aug 2;78(15):7380-97. doi: 10.1021/jo4005487. Epub 2013 Jun 5. J Org Chem. 2013. PMID: 23688199
N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors.
Désiré J, Mondon M, Fontelle N, Nakagawa S, Hirokami Y, Adachi I, Iwaki R, Fleet GW, Alonzi DS, Twigg G, Butters TD, Bertrand J, Cendret V, Becq F, Norez C, Marrot J, Kato A, Blériot Y. Désiré J, et al. Among authors: kato a. Org Biomol Chem. 2014 Nov 28;12(44):8977-96. doi: 10.1039/c4ob00325j. Org Biomol Chem. 2014. PMID: 25277226
Synthesis of 1,2-trans-2-acetamido-2-deoxyhomoiminosugars.
Blériot Y, Tran AT, Prencipe G, Jagadeesh Y, Auberger N, Zhu S, Gauthier C, Zhang Y, Désiré J, Adachi I, Kato A, Sollogoub M. Blériot Y, et al. Among authors: kato a. Org Lett. 2014 Nov 7;16(21):5516-9. doi: 10.1021/ol502929h. Epub 2014 Oct 20. Org Lett. 2014. PMID: 25330462
3,094 results