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Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice.
Parchem JG, Kanasaki K, Kanasaki M, Sugimoto H, Xie L, Hamano Y, Lee SB, Gattone VH, Parry S, Strauss JF, Garovic VD, McElrath TF, Lu KH, Sibai BM, LeBleu VS, Carmeliet P, Kalluri R. Parchem JG, et al. Among authors: kanasaki k, kanasaki m. J Clin Invest. 2018 Nov 1;128(11):5008-5017. doi: 10.1172/JCI99026. Epub 2018 Oct 8. J Clin Invest. 2018. PMID: 30179860 Free PMC article.
Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis.
Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W Jr, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Sugimoto H, et al. Among authors: kanasaki k. Nat Med. 2012 Feb 5;18(3):396-404. doi: 10.1038/nm.2629. Nat Med. 2012. PMID: 22306733 Free PMC article.
Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis.
Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Chen Y, et al. Among authors: kanasaki k. PLoS Biol. 2018 Dec 28;16(12):e2005907. doi: 10.1371/journal.pbio.2005907. eCollection 2018 Dec. PLoS Biol. 2018. PMID: 30592710 Free PMC article.
The biology of preeclampsia.
Kanasaki K, Kalluri R. Kanasaki K, et al. Kidney Int. 2009 Oct;76(8):831-7. doi: 10.1038/ki.2009.284. Epub 2009 Aug 5. Kidney Int. 2009. PMID: 19657323 Free PMC article. Review.
VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation.
Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. Chang SH, et al. Among authors: kanasaki k. Cancer Res. 2009 May 15;69(10):4537-44. doi: 10.1158/0008-5472.CAN-08-4539. Epub 2009 May 12. Cancer Res. 2009. PMID: 19435903 Free PMC article.
161 results