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SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism.
Oishi Y, Spann NJ, Link VM, Muse ED, Strid T, Edillor C, Kolar MJ, Matsuzaka T, Hayakawa S, Tao J, Kaikkonen MU, Carlin AF, Lam MT, Manabe I, Shimano H, Saghatelian A, Glass CK. Oishi Y, et al. Among authors: kaikkonen mu. Cell Metab. 2017 Feb 7;25(2):412-427. doi: 10.1016/j.cmet.2016.11.009. Epub 2016 Dec 29. Cell Metab. 2017. PMID: 28041958 Free PMC article.
Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations.
Aherrahrou R, Baig F, Theofilatos K, Lue D, Beele A, Örd T, Kaikkonen MU, Aherrahrou Z, Cheng Q, Ghosh S, Karnewar S, Karnewar V, Finn A, Owens GK, Joner M, Mayr M, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. medRxiv [Preprint]. 2023 Nov 10:2023.11.10.23298351. doi: 10.1101/2023.11.10.23298351. medRxiv. 2023. PMID: 37986932 Free PMC article. Updated. Preprint.
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium.
Anisimov A, Fang S, Hemanthakumar KA, Örd T, van Avondt K, Chevre R, Toropainen A, Singha P, Gilani H, Nguyen SD, Karaman S, Korhonen EA, Adams RH, Augustin HG, Öörni K, Soehnlein O, Kaikkonen MU, Alitalo K. Anisimov A, et al. Among authors: kaikkonen mu. Nat Cardiovasc Res. 2023 Mar 13;2(3):307-321. doi: 10.1038/s44161-023-00224-y. Nat Cardiovasc Res. 2023. PMID: 37476204 Free PMC article.
Dynamic release of neuronal extracellular vesicles containing miR-21a-5p is induced by hypoxia.
Korvenlaita N, Gómez-Budia M, Scoyni F, Pistono C, Giudice L, Eamen S, Loppi S, de Sande AH, Huremagic B, Bouvy-Liivrand M, Heinäniemi M, Kaikkonen MU, Cheng L, Hill AF, Kanninen KM, Jenster GW, van Royen ME, Ramiro L, Montaner J, Batkova T, Mikulik R, Giugno R, Jolkkonen J, Korhonen P, Malm T. Korvenlaita N, et al. Among authors: kaikkonen mu. J Extracell Vesicles. 2023 Jan;12(1):e12297. doi: 10.1002/jev2.12297. J Extracell Vesicles. 2023. PMID: 36594832 Free PMC article.
Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations.
Aherrahrou R, Baig F, Theofilatos K, Lue D, Beele A, Örd T, Kaikkonen MU, Aherrahrou Z, Cheng Q, Ghosh SKB, Karnewar S, Karnewar V, Finn AV, Owens GK, Joner M, Mayr M, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):898-914. doi: 10.1161/ATVBAHA.123.320274. Epub 2024 Feb 8. Arterioscler Thromb Vasc Biol. 2024. PMID: 38328934
Colchicine promotes atherosclerotic plaque stability independently of inflammation.
Li W, Lin A, Hutton M, Dhaliwal H, Nadel J, Rodor J, Tumanov S, Örd T, Hadden M, Mokry M, Mol BM, Pasterkamp G, Padula MP, Geczy CL, Ramaswamy Y, Sluimer JC, Kaikkonen MU, Stocker R, Baker AH, Fisher EA, Patel S, Misra A. Li W, et al. Among authors: kaikkonen mu. bioRxiv [Preprint]. 2023 Oct 3:2023.10.03.560632. doi: 10.1101/2023.10.03.560632. bioRxiv. 2023. PMID: 37873248 Free PMC article. Preprint.
Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures.
Örd T, Lönnberg T, Nurminen V, Ravindran A, Niskanen H, Kiema M, Õunap K, Maria M, Moreau PR, Mishra PP, Palani S, Virta J, Liljenbäck H, Aavik E, Roivainen A, Ylä-Herttuala S, Laakkonen JP, Lehtimäki T, Kaikkonen MU. Örd T, et al. Among authors: kaikkonen mu. Am J Hum Genet. 2023 May 4;110(5):722-740. doi: 10.1016/j.ajhg.2023.03.013. Epub 2023 Apr 14. Am J Hum Genet. 2023. PMID: 37060905 Free PMC article.
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.
Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. Escoubet-Lozach L, et al. Among authors: kaikkonen mu. PLoS Genet. 2011 Dec;7(12):e1002401. doi: 10.1371/journal.pgen.1002401. Epub 2011 Dec 8. PLoS Genet. 2011. PMID: 22174696 Free PMC article.
114 results