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Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells.
Kobayashi-Ishihara M, Frazão Smutná K, Alonso FE, Argilaguet J, Esteve-Codina A, Geiger K, Genescà M, Grau-Expósito J, Duran-Castells C, Rogenmoser S, Böttcher R, Jungfleisch J, Oliva B, Martinez JP, Li M, David M, Yamagishi M, Ruiz-Riol M, Brander C, Tsunetsugu-Yokota Y, Buzon MJ, Díez J, Meyerhans A. Kobayashi-Ishihara M, et al. Among authors: jungfleisch j. Commun Biol. 2023 May 10;6(1):487. doi: 10.1038/s42003-023-04841-y. Commun Biol. 2023. PMID: 37165099 Free PMC article.
Translation control: Learning from viruses, again.
Díez J, Jungfleisch J. Díez J, et al. Among authors: jungfleisch j. RNA Biol. 2017 Jul 3;14(7):835-837. doi: 10.1080/15476286.2017.1325068. Epub 2017 May 10. RNA Biol. 2017. PMID: 28488947 Free PMC article.
The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.
Blasco-Moreno B, de Campos-Mata L, Böttcher R, García-Martínez J, Jungfleisch J, Nedialkova DD, Chattopadhyay S, Gas ME, Oliva B, Pérez-Ortín JE, Leidel SA, Choder M, Díez J. Blasco-Moreno B, et al. Among authors: jungfleisch j. Nat Commun. 2019 Mar 21;10(1):1298. doi: 10.1038/s41467-019-09199-6. Nat Commun. 2019. PMID: 30899024 Free PMC article.
The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity.
Doñate-Macián P, Jungfleisch J, Pérez-Vilaró G, Rubio-Moscardo F, Perálvarez-Marín A, Diez J, Valverde MA. Doñate-Macián P, et al. Among authors: jungfleisch j. Nat Commun. 2018 Jun 13;9(1):2307. doi: 10.1038/s41467-018-04776-7. Nat Commun. 2018. PMID: 29899501 Free PMC article.