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Page 1
DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions.
Butz S, Schmolka N, Karemaker ID, Villaseñor R, Schwarz I, Domcke S, Uijttewaal ECH, Jude J, Lienert F, Krebs AR, de Wagenaar NP, Bao X, Zuber J, Elling U, Schübeler D, Baubec T. Butz S, et al. Among authors: jude j. Nat Genet. 2022 Nov;54(11):1702-1710. doi: 10.1038/s41588-022-01210-z. Epub 2022 Nov 4. Nat Genet. 2022. PMID: 36333500 Free PMC article.
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Rathert P, Roth M, Neumann T, Muerdter F, Roe JS, Muhar M, Deswal S, Cerny-Reiterer S, Peter B, Jude J, Hoffmann T, Boryń ŁM, Axelsson E, Schweifer N, Tontsch-Grunt U, Dow LE, Gianni D, Pearson M, Valent P, Stark A, Kraut N, Vakoc CR, Zuber J. Rathert P, et al. Among authors: jude j. Nature. 2015 Sep 24;525(7570):543-547. doi: 10.1038/nature14898. Epub 2015 Sep 14. Nature. 2015. PMID: 26367798 Free PMC article.
The histone chaperone CAF-1 safeguards somatic cell identity.
Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, Rathert P, Jude J, Ferrari F, Blanco A, Fellner M, Wenzel D, Zinner M, Vidal SE, Bell O, Stadtfeld M, Chang HY, Almouzni G, Lowe SW, Rinn J, Wernig M, Aravin A, Shi Y, Park PJ, Penninger JM, Zuber J, Hochedlinger K. Cheloufi S, et al. Among authors: jude j. Nature. 2015 Dec 10;528(7581):218-24. doi: 10.1038/nature15749. Nature. 2015. PMID: 26659182 Free PMC article.
A vital sugar code for ricin toxicity.
Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM. Taubenschmid J, et al. Among authors: jude j. Cell Res. 2017 Nov;27(11):1351-1364. doi: 10.1038/cr.2017.116. Epub 2017 Sep 19. Cell Res. 2017. PMID: 28925387 Free PMC article.
MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.
Skucha A, Ebner J, Schmöllerl J, Roth M, Eder T, César-Razquin A, Stukalov A, Vittori S, Muhar M, Lu B, Aichinger M, Jude J, Müller AC, Győrffy B, Vakoc CR, Valent P, Bennett KL, Zuber J, Superti-Furga G, Grebien F. Skucha A, et al. Among authors: jude j. Nat Commun. 2018 May 18;9(1):1983. doi: 10.1038/s41467-018-04329-y. Nat Commun. 2018. PMID: 29777171 Free PMC article.
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.
Michlits G, Jude J, Hinterndorfer M, de Almeida M, Vainorius G, Hubmann M, Neumann T, Schleiffer A, Burkard TR, Fellner M, Gijsbertsen M, Traunbauer A, Zuber J, Elling U. Michlits G, et al. Among authors: jude j. Nat Methods. 2020 Jul;17(7):708-716. doi: 10.1038/s41592-020-0850-8. Epub 2020 Jun 8. Nat Methods. 2020. PMID: 32514112
Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters.
Umkehrer C, Holstein F, Formenti L, Jude J, Froussios K, Neumann T, Cronin SM, Haas L, Lipp JJ, Burkard TR, Fellner M, Wiesner T, Zuber J, Obenauf AC. Umkehrer C, et al. Among authors: jude j. Nat Biotechnol. 2021 Feb;39(2):174-178. doi: 10.1038/s41587-020-0614-0. Epub 2020 Jul 27. Nat Biotechnol. 2021. PMID: 32719478
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida M, Hinterndorfer M, Brunner H, Grishkovskaya I, Singh K, Schleiffer A, Jude J, Deswal S, Kalis R, Vunjak M, Lendl T, Imre R, Roitinger E, Neumann T, Kandolf S, Schutzbier M, Mechtler K, Versteeg GA, Haselbach D, Zuber J. de Almeida M, et al. Among authors: jude j. Nature. 2021 Nov;599(7885):491-496. doi: 10.1038/s41586-021-04035-8. Epub 2021 Oct 28. Nature. 2021. PMID: 34711951
195 results