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Discovery of small molecules that target a tertiary-structured RNA.
Menichelli E, Lam BJ, Wang Y, Wang VS, Shaffer J, Tjhung KF, Bursulaya B, Nguyen TN, Vo T, Alper PB, McAllister CS, Jones DH, Spraggon G, Michellys PY, Joslin J, Joyce GF, Rogers J. Menichelli E, et al. Among authors: joyce gf. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2213117119. doi: 10.1073/pnas.2213117119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36413497 Free PMC article.
A ribozyme that lacks cytidine.
Rogers J, Joyce GF. Rogers J, et al. Among authors: joyce gf. Nature. 1999 Nov 18;402(6759):323-5. doi: 10.1038/46335. Nature. 1999. PMID: 10580507
Binding of a structured D-RNA molecule by an L-RNA aptamer.
Sczepanski JT, Joyce GF. Sczepanski JT, et al. Among authors: joyce gf. J Am Chem Soc. 2013 Sep 11;135(36):13290-3. doi: 10.1021/ja406634g. Epub 2013 Aug 28. J Am Chem Soc. 2013. PMID: 23977945 Free PMC article.
Amplification of RNA by an RNA polymerase ribozyme.
Horning DP, Joyce GF. Horning DP, et al. Among authors: joyce gf. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):9786-91. doi: 10.1073/pnas.1610103113. Epub 2016 Aug 15. Proc Natl Acad Sci U S A. 2016. PMID: 27528667 Free PMC article.
An RNA polymerase ribozyme that synthesizes its own ancestor.
Tjhung KF, Shokhirev MN, Horning DP, Joyce GF. Tjhung KF, et al. Among authors: joyce gf. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2906-2913. doi: 10.1073/pnas.1914282117. Epub 2020 Jan 27. Proc Natl Acad Sci U S A. 2020. PMID: 31988127 Free PMC article.
RNA-Catalyzed Cross-Chiral Polymerization of RNA.
Tjhung KF, Sczepanski JT, Murtfeldt ER, Joyce GF. Tjhung KF, et al. Among authors: joyce gf. J Am Chem Soc. 2020 Sep 9;142(36):15331-15339. doi: 10.1021/jacs.0c05635. Epub 2020 Aug 26. J Am Chem Soc. 2020. PMID: 32805113
188 results