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Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
ACS Chem Biol. 2024 Jan 19;19(1):141-152. doi: 10.1021/acschembio.3c00568. Epub 2023 Dec 12.
ACS Chem Biol. 2024.
PMID: 38085789
Probing Ligand Binding Sites on Large Proteins by Nuclear Magnetic Resonance Spectroscopy of Genetically Encoded Non-Canonical Amino Acids.
Ekanayake KB, Mahawaththa MC, Qianzhu H, Abdelkader EH, George J, Ullrich S, Murphy RB, Fry SE, Johansen-Leete J, Payne RJ, Nitsche C, Huber T, Otting G.
Ekanayake KB, et al. Among authors: johansen leete j.
J Med Chem. 2023 Apr 13;66(7):5289-5304. doi: 10.1021/acs.jmedchem.3c00222. Epub 2023 Mar 15.
J Med Chem. 2023.
PMID: 36920850
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Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening.
Sasi VM, Ullrich S, Ton J, Fry SE, Johansen-Leete J, Payne RJ, Nitsche C, Jackson CJ.
Sasi VM, et al. Among authors: johansen leete j.
Biochemistry. 2022 Nov 15;61(22):2495-2505. doi: 10.1021/acs.biochem.2c00489. Epub 2022 Nov 3.
Biochemistry. 2022.
PMID: 36326185
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Expressed Protein Selenoester Ligation.
Kulkarni SS, Watson EE, Maxwell JWC, Niederacher G, Johansen-Leete J, Huhmann S, Mukherjee S, Norman AR, Kriegesmann J, Becker CFW, Payne RJ.
Kulkarni SS, et al. Among authors: johansen leete j.
Angew Chem Weinheim Bergstr Ger. 2022 May 9;134(20):e202200163. doi: 10.1002/ange.202200163. Epub 2022 Mar 9.
Angew Chem Weinheim Bergstr Ger. 2022.
PMID: 38505698
Free PMC article.
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Antiviral cyclic peptides targeting the main protease of SARS-CoV-2.
Johansen-Leete J, Ullrich S, Fry SE, Frkic R, Bedding MJ, Aggarwal A, Ashhurst AS, Ekanayake KB, Mahawaththa MC, Sasi VM, Luedtke S, Ford DJ, O'Donoghue AJ, Passioura T, Larance M, Otting G, Turville S, Jackson CJ, Nitsche C, Payne RJ.
Johansen-Leete J, et al.
Chem Sci. 2022 Feb 28;13(13):3826-3836. doi: 10.1039/d1sc06750h. eCollection 2022 Mar 30.
Chem Sci. 2022.
PMID: 35432913
Free PMC article.
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Expressed Protein Selenoester Ligation.
Kulkarni SS, Watson EE, Maxwell JWC, Niederacher G, Johansen-Leete J, Huhmann S, Mukherjee S, Norman AR, Kriegesmann J, Becker CFW, Payne RJ.
Kulkarni SS, et al. Among authors: johansen leete j.
Angew Chem Int Ed Engl. 2022 May 9;61(20):e202200163. doi: 10.1002/anie.202200163. Epub 2022 Mar 9.
Angew Chem Int Ed Engl. 2022.
PMID: 35194928
Free PMC article.
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Semisynthesis of an evasin from tick saliva reveals a critical role of tyrosine sulfation for chemokine binding and inhibition.
Franck C, Foster SR, Johansen-Leete J, Chowdhury S, Cielesh M, Bhusal RP, Mackay JP, Larance M, Stone MJ, Payne RJ.
Franck C, et al. Among authors: johansen leete j.
Proc Natl Acad Sci U S A. 2020 Jun 9;117(23):12657-12664. doi: 10.1073/pnas.2000605117. Epub 2020 May 27.
Proc Natl Acad Sci U S A. 2020.
PMID: 32461364
Free PMC article.
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Discovery of Potent Cyclic Sulfopeptide Chemokine Inhibitors via Reprogrammed Genetic Code mRNA Display.
Johansen-Leete J, Passioura T, Foster SR, Bhusal RP, Ford DJ, Liu M, Jongkees SAK, Suga H, Stone MJ, Payne RJ.
Johansen-Leete J, et al.
J Am Chem Soc. 2020 May 20;142(20):9141-9146. doi: 10.1021/jacs.0c03152. Epub 2020 May 7.
J Am Chem Soc. 2020.
PMID: 32330017
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