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Pneumococcal colonization impairs mucosal immune responses to live attenuated influenza vaccine.
Carniel BF, Marcon F, Rylance J, German EL, Zaidi S, Reiné J, Negera E, Nikolaou E, Pojar S, Solórzano C, Collins AM, Connor V, Bogaert D, Gordon SB, Nakaya HI, Ferreira DM, Jochems SP, Mitsi E. Carniel BF, et al. Among authors: jochems sp. JCI Insight. 2021 Feb 22;6(4):e141088. doi: 10.1172/jci.insight.141088. JCI Insight. 2021. PMID: 33497364 Free PMC article. Clinical Trial.
Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.
Jochems SP, Piddock K, Rylance J, Adler H, Carniel BF, Collins A, Gritzfeld JF, Hancock C, Hill H, Reiné J, Seddon A, Solórzano C, Sunny S, Trimble A, Wright AD, Zaidi S, Gordon SB, Ferreira DM. Jochems SP, et al. PLoS One. 2017 Jan 20;12(1):e0169805. doi: 10.1371/journal.pone.0169805. eCollection 2017. PLoS One. 2017. PMID: 28107457 Free PMC article.
The immunological mechanisms that control pneumococcal carriage.
Jochems SP, Weiser JN, Malley R, Ferreira DM. Jochems SP, et al. PLoS Pathog. 2017 Dec 21;13(12):e1006665. doi: 10.1371/journal.ppat.1006665. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29267378 Free PMC article. Review.
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.
Connor V, German E, Pojar S, Mitsi E, Hales C, Nikolaou E, Hyder-Wright A, Adler H, Zaidi S, Hill H, Jochems SP, Burhan H, French N, Tobery T, Rylance J, Ferreira DM. Connor V, et al. Among authors: jochems sp. Eur Respir J. 2018 Oct 10;52(4):1800599. doi: 10.1183/13993003.00599-2018. Print 2018 Oct. Eur Respir J. 2018. PMID: 30305331 Free article. No abstract available.
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.
Jochems SP, Marcon F, Carniel BF, Holloway M, Mitsi E, Smith E, Gritzfeld JF, Solórzano C, Reiné J, Pojar S, Nikolaou E, German EL, Hyder-Wright A, Hill H, Hales C, de Steenhuijsen Piters WAA, Bogaert D, Adler H, Zaidi S, Connor V, Gordon SB, Rylance J, Nakaya HI, Ferreira DM. Jochems SP, et al. Nat Immunol. 2018 Dec;19(12):1299-1308. doi: 10.1038/s41590-018-0231-y. Epub 2018 Oct 29. Nat Immunol. 2018. PMID: 30374129 Free PMC article. Clinical Trial.
Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine.
de Steenhuijsen Piters WAA, Jochems SP, Mitsi E, Rylance J, Pojar S, Nikolaou E, German EL, Holloway M, Carniel BF, Chu MLJN, Arp K, Sanders EAM, Ferreira DM, Bogaert D. de Steenhuijsen Piters WAA, et al. Among authors: jochems sp. Nat Commun. 2019 Jul 5;10(1):2981. doi: 10.1038/s41467-019-10814-9. Nat Commun. 2019. PMID: 31278315 Free PMC article.
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.
Jochems SP, de Ruiter K, Solórzano C, Voskamp A, Mitsi E, Nikolaou E, Carniel BF, Pojar S, German EL, Reiné J, Soares-Schanoski A, Hill H, Robinson R, Hyder-Wright AD, Weight CM, Durrenberger PF, Heyderman RS, Gordon SB, Smits HH, Urban BC, Rylance J, Collins AM, Wilkie MD, Lazarova L, Leong SC, Yazdanbakhsh M, Ferreira DM. Jochems SP, et al. J Clin Invest. 2019 Jul 30;129(10):4523-4538. doi: 10.1172/JCI128865. J Clin Invest. 2019. PMID: 31361601 Free PMC article. Clinical Trial.
Nasal Pneumococcal Density Is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.
Mitsi E, Carniel B, Reiné J, Rylance J, Zaidi S, Soares-Schanoski A, Connor V, Collins AM, Schlitzer A, Nikolaou E, Solórzano C, Pojar S, Hill H, Hyder-Wright AD, Jambo KC, Oggioni MR, De Ste Croix M, Gordon SB, Jochems SP, Ferreira DM. Mitsi E, et al. Among authors: jochems sp. Am J Respir Crit Care Med. 2020 Feb 1;201(3):335-347. doi: 10.1164/rccm.201903-0607OC. Am J Respir Crit Care Med. 2020. PMID: 31626559 Free PMC article.
51 results