Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection

Pediatr Infect Dis J. 2019 Nov;38(11):1147-1149. doi: 10.1097/INF.0000000000002454.

Abstract

Nasopharyngeal colonization of potential respiratory pathogens such as Streptococcus pneumoniae is the major source of transmission and precursor of invasive disease. Swabbing deeply the nasopharynx, which is currently recommended by World Health Organization, provides accurate pneumococcal detection but is unpleasant. We showed that nasal lining fluid filter strips offer equal detection sensitivity.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriological Techniques / methods
  • Carrier State / microbiology*
  • Child, Preschool
  • Humans
  • Infant
  • Nose / microbiology
  • Pneumococcal Infections / diagnosis*
  • Pneumococcal Infections / microbiology
  • Reagent Strips*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Specimen Handling / instrumentation*
  • Specimen Handling / methods*
  • Streptococcus pneumoniae / isolation & purification*

Substances

  • Reagent Strips