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NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome.
Fang EF, Hou Y, Lautrup S, Jensen MB, Yang B, SenGupta T, Caponio D, Khezri R, Demarest TG, Aman Y, Figueroa D, Morevati M, Lee HJ, Kato H, Kassahun H, Lee JH, Filippelli D, Okur MN, Mangerich A, Croteau DL, Maezawa Y, Lyssiotis CA, Tao J, Yokote K, Rusten TE, Mattson MP, Jasper H, Nilsen H, Bohr VA. Fang EF, et al. Among authors: jasper h. Nat Commun. 2019 Nov 21;10(1):5284. doi: 10.1038/s41467-019-13172-8. Nat Commun. 2019. PMID: 31754102 Free PMC article.
Sirtuins: Longevity focuses on NAD+.
Jasper H. Jasper H. Nat Chem Biol. 2013 Nov;9(11):666-7. doi: 10.1038/nchembio.1369. Nat Chem Biol. 2013. PMID: 24141218 No abstract available.
Mutations of mitochondrial DNA are not major contributors to aging of fruit flies.
Kauppila TES, Bratic A, Jensen MB, Baggio F, Partridge L, Jasper H, Grönke S, Larsson NG. Kauppila TES, et al. Among authors: jasper h. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9620-E9629. doi: 10.1073/pnas.1721683115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249665 Free PMC article.
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth.
Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE. Khezri R, et al. Among authors: jasper h. EMBO J. 2021 Sep 15;40(18):e107336. doi: 10.15252/embj.2020107336. Epub 2021 Jul 26. EMBO J. 2021. PMID: 34309071 Free PMC article.
Aging: seeking mitonuclear balance.
Karpac J, Jasper H. Karpac J, et al. Among authors: jasper h. Cell. 2013 Jul 18;154(2):271-3. doi: 10.1016/j.cell.2013.06.046. Cell. 2013. PMID: 23870118 Free article.
365 results