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CinA mediates multidrug tolerance in Mycobacterium tuberculosis.
Kreutzfeldt KM, Jansen RS, Hartman TE, Gouzy A, Wang R, Krieger IV, Zimmerman MD, Gengenbacher M, Sarathy JP, Xie M, Dartois V, Sacchettini JC, Rhee KY, Schnappinger D, Ehrt S. Kreutzfeldt KM, et al. Among authors: jansen rs. Nat Commun. 2022 Apr 22;13(1):2203. doi: 10.1038/s41467-022-29832-1. Nat Commun. 2022. PMID: 35459278 Free PMC article.
Metabolic Perspectives on Persistence.
Hartman TE, Wang Z, Jansen RS, Gardete S, Rhee KY. Hartman TE, et al. Among authors: jansen rs. Microbiol Spectr. 2017 Jan;5(1):10.1128/microbiolspec.TBTB2-0026-2016. doi: 10.1128/microbiolspec.TBTB2-0026-2016. Microbiol Spectr. 2017. PMID: 28155811 Free PMC article. Review.
Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis.
Chen C, Gardete S, Jansen RS, Shetty A, Dick T, Rhee KY, Dartois V. Chen C, et al. Among authors: jansen rs. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02107-17. doi: 10.1128/AAC.02107-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29463541 Free PMC article.
Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions.
Ginn J, Jiang X, Sun S, Michino M, Huggins DJ, Mbambo Z, Jansen R, Rhee KY, Arango N, Lima CD, Liverton N, Imaeda T, Okamoto R, Kuroita T, Aso K, Stamford A, Foley M, Meinke PT, Nathan C, Bryk R. Ginn J, et al. ACS Infect Dis. 2021 Feb 12;7(2):435-444. doi: 10.1021/acsinfecdis.0c00788. Epub 2021 Feb 2. ACS Infect Dis. 2021. PMID: 33527832 Free PMC article.
Multiform antimicrobial resistance from a metabolic mutation.
Schrader SM, Botella H, Jansen R, Ehrt S, Rhee K, Nathan C, Vaubourgeix J. Schrader SM, et al. Sci Adv. 2021 Aug 27;7(35):eabh2037. doi: 10.1126/sciadv.abh2037. Print 2021 Aug. Sci Adv. 2021. PMID: 34452915 Free PMC article.
51 results