James LC - Search Results

1

Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.

Stacey JCV, Tan A, Lu JM, James LC, Dick RA, Briggs JAG. Stacey JCV, et al. Among authors: james lc. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2220557120. doi: 10.1073/pnas.2220557120. Epub 2023 Apr 11. Proc Natl Acad Sci U S A. 2023. PMID: 37040417 Free PMC article.

2

Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition.

James LC, Tawfik DS. James LC, et al. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12730-5. doi: 10.1073/pnas.0500909102. Epub 2005 Aug 29. Proc Natl Acad Sci U S A. 2005. PMID: 16129832 Free PMC article.

3

CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.

Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, KewalRamani VN, Chin JW, Towers GJ, James LC. Price AJ, et al. Among authors: james lc. PLoS Pathog. 2012;8(8):e1002896. doi: 10.1371/journal.ppat.1002896. Epub 2012 Aug 30. PLoS Pathog. 2012. PMID: 22956906 Free PMC article.

4

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

Price AJ, Jacques DA, McEwan WA, Fletcher AJ, Essig S, Chin JW, Halambage UD, Aiken C, James LC. Price AJ, et al. Among authors: james lc. PLoS Pathog. 2014 Oct 30;10(10):e1004459. doi: 10.1371/journal.ppat.1004459. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25356722 Free PMC article.

5

HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.

Zhou J, Price AJ, Halambage UD, James LC, Aiken C. Zhou J, et al. Among authors: james lc. J Virol. 2015 Sep;89(17):9068-79. doi: 10.1128/JVI.00340-15. Epub 2015 Jun 24. J Virol. 2015. PMID: 26109731 Free PMC article.

6

IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.

Mallery DL, Márquez CL, McEwan WA, Dickson CF, Jacques DA, Anandapadamanaban M, Bichel K, Towers GJ, Saiardi A, Böcking T, James LC. Mallery DL, et al. Among authors: james lc. Elife. 2018 May 31;7:e35335. doi: 10.7554/eLife.35335. Elife. 2018. PMID: 29848441 Free PMC article.

7

IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating.

Dick RA, Mallery DL, Vogt VM, James LC. Dick RA, et al. Among authors: james lc. Viruses. 2018 Nov 15;10(11):640. doi: 10.3390/v10110640. Viruses. 2018. PMID: 30445742 Free PMC article. Review.

8

The HIV-1 Capsid: More than Just a Delivery Package.

James LC. James LC. Adv Exp Med Biol. 2019;1215:69-83. doi: 10.1007/978-3-030-14741-9_4. Adv Exp Med Biol. 2019. PMID: 31317496

9

Building Complexity: Making and Breaking Synthetic Subunits of the HIV Capsid.

James LC, Böcking T. James LC, et al. Cell Host Microbe. 2019 Aug 14;26(2):151-153. doi: 10.1016/j.chom.2019.07.011. Cell Host Microbe. 2019. PMID: 31415744 Free article.

10

A thermostable, closed SARS-CoV-2 spike protein trimer.

Xiong X, Qu K, Ciazynska KA, Hosmillo M, Carter AP, Ebrahimi S, Ke Z, Scheres SHW, Bergamaschi L, Grice GL, Zhang Y; CITIID-NIHR COVID-19 BioResource Collaboration; Nathan JA, Baker S, James LC, Baxendale HE, Goodfellow I, Doffinger R, Briggs JAG. Xiong X, et al. Among authors: james lc. Nat Struct Mol Biol. 2020 Oct;27(10):934-941. doi: 10.1038/s41594-020-0478-5. Epub 2020 Jul 31. Nat Struct Mol Biol. 2020. PMID: 32737467 Free PMC article.

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