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Year Number of Results
2010 1
2012 1
2013 1
2014 3
2015 6
2016 4
2017 4
2018 5
2019 4
2020 6
2021 4
2022 1
2023 2
2024 0

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36 results

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Page 1
2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators.
Marcinkowska M, Fajkis-Zajączkowska N, Szafrańska K, Jończyk J, Siwek A, Mordyl B, Karcz T, Latacz G, Kolaczkowski M. Marcinkowska M, et al. Among authors: jonczyk j. ACS Chem Neurosci. 2023 Mar 15;14(6):1166-1180. doi: 10.1021/acschemneuro.2c00800. Epub 2023 Feb 27. ACS Chem Neurosci. 2023. PMID: 36848624 Free PMC article.
New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease.
Czarnecka K, Girek M, Kręcisz P, Skibiński R, Łątka K, Jończyk J, Bajda M, Szymczyk P, Galita G, Kabziński J, Majsterek I, Espargaró A, Sabate R, Szymański P. Czarnecka K, et al. Among authors: jonczyk j. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2158822. doi: 10.1080/14756366.2022.2158822. J Enzyme Inhib Med Chem. 2023. PMID: 36629422 Free PMC article.
Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.
Pasieka A, Panek D, Jończyk J, Godyń J, Szałaj N, Latacz G, Tabor J, Mezeiova E, Chantegreil F, Dias J, Knez D, Lu J, Pi R, Korabecny J, Brazzolotto X, Gobec S, Höfner G, Wanner K, Więckowska A, Malawska B. Pasieka A, et al. Among authors: jonczyk j. Eur J Med Chem. 2021 Jun 5;218:113397. doi: 10.1016/j.ejmech.2021.113397. Epub 2021 Mar 31. Eur J Med Chem. 2021. PMID: 33838585
Pyridinium-2-carbaldoximes with quinolinium carboxamide moiety are simultaneous reactivators of acetylcholinesterase and butyrylcholinesterase inhibited by nerve agent surrogates.
Lee HM, Andrys R, Jonczyk J, Kim K, Vishakantegowda AG, Malinak D, Skarka A, Schmidt M, Vaskova M, Latka K, Bajda M, Jung YS, Malawska B, Musilek K. Lee HM, et al. Among authors: jonczyk j. J Enzyme Inhib Med Chem. 2021 Dec;36(1):437-449. doi: 10.1080/14756366.2020.1869954. J Enzyme Inhib Med Chem. 2021. PMID: 33467931 Free PMC article.
Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease.
Szałaj N, Godyń J, Jończyk J, Pasieka A, Panek D, Wichur T, Więckowski K, Zaręba P, Bajda M, Pislar A, Malawska B, Sabate R, Więckowska A. Szałaj N, et al. Among authors: jonczyk j. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1944-1952. doi: 10.1080/14756366.2020.1835882. J Enzyme Inhib Med Chem. 2020. PMID: 33092411 Free PMC article.
New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease.
Czarnecka K, Girek M, Wójtowicz P, Kręcisz P, Skibiński R, Jończyk J, Łątka K, Bajda M, Walczak A, Galita G, Kabziński J, Majsterek I, Szymczyk P, Szymański P. Czarnecka K, et al. Among authors: jonczyk j. Int J Mol Sci. 2020 May 26;21(11):3765. doi: 10.3390/ijms21113765. Int J Mol Sci. 2020. PMID: 32466601 Free PMC article.
36 results