Iwatsubo T - Search Results

1

The Amyloid-β Pathway in Alzheimer's Disease.

Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. Hampel H, et al. Among authors: iwatsubo t. Mol Psychiatry. 2021 Oct;26(10):5481-5503. doi: 10.1038/s41380-021-01249-0. Epub 2021 Aug 30. Mol Psychiatry. 2021. PMID: 34456336 Free PMC article. Review.

2

CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV.

Hashimoto T, Wakabayashi T, Watanabe A, Kowa H, Hosoda R, Nakamura A, Kanazawa I, Arai T, Takio K, Mann DM, Iwatsubo T. Hashimoto T, et al. Among authors: iwatsubo t. EMBO J. 2002 Apr 2;21(7):1524-34. doi: 10.1093/emboj/21.7.1524. EMBO J. 2002. PMID: 11927537 Free PMC article.

3

[The mechanism of A beta production and its inhibition as a therapeutic strategy for the prevention of Alzheimer's disease].

Iwatsubo T. Iwatsubo T. Nihon Yakurigaku Zasshi. 2002 Nov;120(1):30P-33P. Nihon Yakurigaku Zasshi. 2002. PMID: 12491772 Review. Japanese.

4

Molecular pathogenesis of Alzheimer's disease.

Iwatsubo T. Iwatsubo T. Intern Med. 2003 Mar;42(3):312. Intern Med. 2003. PMID: 12705809 Free article. No abstract available.

5

Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol.

Abe Y, Kouyama K, Tomita T, Tomita Y, Ban N, Nawa M, Matsuoka M, Niikura T, Aiso S, Kita Y, Iwatsubo T, Nishimoto I. Abe Y, et al. Among authors: iwatsubo t. J Neurosci. 2003 Sep 17;23(24):8513-25. doi: 10.1523/JNEUROSCI.23-24-08513.2003. J Neurosci. 2003. PMID: 13679420 Free PMC article.

6

Assembly and activation of the gamma-secretase complex: roles of presenilin cofactors.

Iwatsubo T. Iwatsubo T. Mol Psychiatry. 2004 Jan;9(1):8-10. doi: 10.1038/sj.mp.4001438. Mol Psychiatry. 2004. PMID: 14581930 Review. No abstract available.

7

Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.

Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, Al-Saraj S, Killick R, Pickering-Brown S, Moore P, Hollingworth P, Archer N, Foy C, Walter S, Lendon C, Iwatsubo T, Morris JC, Norton J, Mann D, Janssens B, Hardy J, O'Donovan M, Jones L, Williams J, Holmans P, Owen MJ, Grupe A, Powell J, van Hengel J, Goate A, Van Roy F, Lovestone S. Busby V, et al. Among authors: iwatsubo t. Neuromolecular Med. 2004;5(2):133-46. doi: 10.1385/NMM:5:2:133. Neuromolecular Med. 2004. PMID: 15075440

8

Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.

Kawasumi M, Chiba T, Yamada M, Miyamae-Kaneko M, Matsuoka M, Nakahara J, Tomita T, Iwatsubo T, Kato S, Aiso S, Nishimoto I, Kouyama K. Kawasumi M, et al. Among authors: iwatsubo t. Eur J Neurosci. 2004 May;19(10):2826-38. doi: 10.1111/j.0953-816X.2004.03397.x. Eur J Neurosci. 2004. PMID: 15147316

9

The inhibition of gamma-secretase as a therapeutic approach to Alzheimer's disease.

Tomita T, Iwatsubo T. Tomita T, et al. Among authors: iwatsubo t. Drug News Perspect. 2004 Jun;17(5):321-5. doi: 10.1358/dnp.2004.17.5.829036. Drug News Perspect. 2004. PMID: 15334182 Review.

10

[Recent advances in Alzheimer's disease-related gamma-secretase complex].

Tomita T, Iwatsubo T. Tomita T, et al. Among authors: iwatsubo t. Seikagaku. 2004 Jul;76(7):666-70. Seikagaku. 2004. PMID: 15346905 Review. Japanese. No abstract available.

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