[Recent advances in Alzheimer's disease-related gamma-secretase complex]

Seikagaku. 2004 Jul;76(7):666-70.

[Article in Japanese]

Authors

Taisuke Tomita¹, Takeshi Iwatsubo

Affiliation

¹ Department of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, University of Tokyo, 7-3-1, Hongo, Bunkyo, Tokyo 113-0033, Japan.

PMID: 15346905

No abstract available

Publication types

Review

MeSH terms

Alzheimer Disease / drug therapy
Alzheimer Disease / etiology*
Amyloid Precursor Protein Secretases
Amyloid beta-Peptides / biosynthesis
Amyloid beta-Protein Precursor / metabolism
Aspartic Acid Endopeptidases
Drug Design
Endopeptidases* / physiology
Enzyme Inhibitors / therapeutic use
Humans

Substances

Amyloid beta-Peptides
Amyloid beta-Protein Precursor
Enzyme Inhibitors
Amyloid Precursor Protein Secretases
Endopeptidases
Aspartic Acid Endopeptidases
BACE1 protein, human