Ismail IH - Search Results

1

Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents.

Rashed FB, Diaz-Dussan D, Mashayekhi F, Macdonald D, Nation PN, Yang XH, Sokhi S, Stoica AC, El-Saidi H, Ricardo C, Narain R, Ismail IH, Wiebe LI, Kumar P, Weinfeld M. Rashed FB, et al. Among authors: ismail ih. Redox Biol. 2022 Jun;52:102300. doi: 10.1016/j.redox.2022.102300. Epub 2022 Mar 21. Redox Biol. 2022. PMID: 35430547 Free PMC article.

2

SUMOylation mediates CtIP's functions in DNA end resection and replication fork protection.

Locke AJ, Hossain L, McCrostie G, Ronato DA, Fitieh A, Rafique TA, Mashayekhi F, Motamedi M, Masson JY, Ismail IH. Locke AJ, et al. Among authors: ismail ih. Nucleic Acids Res. 2021 Jan 25;49(2):928-953. doi: 10.1093/nar/gkaa1232. Nucleic Acids Res. 2021. PMID: 33406258 Free PMC article.

3

BMI-1 regulates DNA end resection and homologous recombination repair.

Fitieh A, Locke AJ, Mashayekhi F, Khaliqdina F, Sharma AK, Ismail IH. Fitieh A, et al. Among authors: ismail ih. Cell Rep. 2022 Mar 22;38(12):110536. doi: 10.1016/j.celrep.2022.110536. Cell Rep. 2022. PMID: 35320715 Free article.

4

Unravelling the Role of PARP1 in Homeostasis and Tumorigenesis: Implications for Anti-Cancer Therapies and Overcoming Resistance.

Lovsund T, Mashayekhi F, Fitieh A, Stafford J, Ismail IH. Lovsund T, et al. Among authors: ismail ih. Cells. 2023 Jul 21;12(14):1904. doi: 10.3390/cells12141904. Cells. 2023. PMID: 37508568 Free PMC article. Review.

5

The role of RNF138 in DNA end resection is regulated by ubiquitylation and CDK phosphorylation.

Locke AJ, Abou Farraj R, Tran C, Zeinali E, Mashayekhi F, Ali JYH, Glover JNM, Ismail IH. Locke AJ, et al. Among authors: ismail ih. J Biol Chem. 2024 Mar;300(3):105709. doi: 10.1016/j.jbc.2024.105709. Epub 2024 Feb 1. J Biol Chem. 2024. PMID: 38309501 Free PMC article.

6

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair.

Ismail IH, Andrin C, McDonald D, Hendzel MJ. Ismail IH, et al. J Cell Biol. 2010 Oct 4;191(1):45-60. doi: 10.1083/jcb.201003034. J Cell Biol. 2010. PMID: 20921134 Free PMC article.

7

The Role of DNA Repair in Genomic Instability of Multiple Myeloma.

Ali JYH, Fitieh AM, Ismail IH. Ali JYH, et al. Among authors: ismail ih. Int J Mol Sci. 2022 May 19;23(10):5688. doi: 10.3390/ijms23105688. Int J Mol Sci. 2022. PMID: 35628498 Free PMC article. Review.

8

Germline mutations in BAP1 impair its function in DNA double-strand break repair.

Ismail IH, Davidson R, Gagné JP, Xu ZZ, Poirier GG, Hendzel MJ. Ismail IH, et al. Cancer Res. 2014 Aug 15;74(16):4282-94. doi: 10.1158/0008-5472.CAN-13-3109. Epub 2014 Jun 3. Cancer Res. 2014. PMID: 24894717

9

The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice.

Ismail IH, Gagné JP, Genois MM, Strickfaden H, McDonald D, Xu Z, Poirier GG, Masson JY, Hendzel MJ. Ismail IH, et al. Nat Cell Biol. 2015 Nov;17(11):1446-57. doi: 10.1038/ncb3259. Epub 2015 Oct 26. Nat Cell Biol. 2015. PMID: 26502055

10

BCL10 is recruited to sites of DNA damage to facilitate DNA double-strand break repair.

Ismail IH, Dronyk A, Hu X, Hendzel MJ, Shaw AR. Ismail IH, et al. Cell Cycle. 2016;15(1):84-94. doi: 10.1080/15384101.2015.1121322. Cell Cycle. 2016. PMID: 26771713 Free PMC article.

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