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Activation of lysosomal iron triggers ferroptosis in cancer.
Rodriguez R, Cañeque T, Baron L, Müller S, Carmona A, Colombeau L, Versini A, Sabatier M, Sampaio J, Mishima E, Picard-Bernes A, Solier S, Zheng J, Proneth B, Thoidingjam L, Gaillet C, Grimaud L, Fraser C, Szylo K, Bonnet C, Charafe E, Ginestier C, Santofimia P, Dusetti N, Iovanna J, Sa Cunha A, Pittau G, Hammel P, Tzanis D, Bonvalot S, Watson S, Stockwell B, Conrad M, Ubellacker J. Rodriguez R, et al. Among authors: iovanna j. Res Sq [Preprint]. 2024 Apr 8:rs.3.rs-4165774. doi: 10.21203/rs.3.rs-4165774/v1. Res Sq. 2024. PMID: 38659936 Free PMC article. Preprint.
EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas.
Pollin G, Mathison AJ, de Assuncao TM, Thomas A, Zeighami L, Salmonson A, Liu H, Urrutia G, Vankayala P, Pandol SJ, Zimmermann MT, Iovanna J, Jin VX, Urrutia R, Lomberk G. Pollin G, et al. Among authors: iovanna j. bioRxiv [Preprint]. 2024 Mar 16:2024.03.14.584700. doi: 10.1101/2024.03.14.584700. bioRxiv. 2024. PMID: 38529489 Free PMC article. Preprint.
A guideline on the molecular ecosystem regulating ferroptosis.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Liu J, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi JT, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. Dai E, et al. Among authors: iovanna j. Nat Cell Biol. 2024 Feb 29. doi: 10.1038/s41556-024-01360-8. Online ahead of print. Nat Cell Biol. 2024. PMID: 38424270 Review.
Targeting NUPR1-dependent stress granules formation to induce synthetic lethality in KrasG12D-driven tumors.
Santofimia-Castaño P, Fraunhoffer N, Liu X, Bessone IF, di Magliano MP, Audebert S, Camoin L, Estaras M, Brenière M, Modesti M, Lomberk G, Urrutia R, Soubeyran P, Neira JL, Iovanna J. Santofimia-Castaño P, et al. Among authors: iovanna j. EMBO Mol Med. 2024 Mar;16(3):475-505. doi: 10.1038/s44321-024-00032-2. Epub 2024 Feb 15. EMBO Mol Med. 2024. PMID: 38360999 Free PMC article.
Prediction of Adjuvant Gemcitabine Sensitivity in Resectable Pancreatic Adenocarcinoma Using the GemPred RNA Signature: An Ancillary Study of the PRODIGE-24/CCTG PA6 Clinical Trial.
Nicolle R, Bachet JB, Harlé A, Iovanna J, Hammel P, Rebours V, Turpin A, Ben Abdelghani M, Wei A, Mitry E, Lopez A, Biagi J, François E, Artru P, Lambert A, Renouf DJ, Monard L, Mauduit M, Dusetti N, Conroy T, Cros J. Nicolle R, et al. Among authors: iovanna j. J Clin Oncol. 2024 Mar 20;42(9):1067-1076. doi: 10.1200/JCO.22.02668. Epub 2023 Nov 14. J Clin Oncol. 2024. PMID: 37963313 Free PMC article.
[The mRNA vaccine for the treatment of pancreatic cancer is here to stay].
Chuluyan E, Davio C, Dusetti N, Fraunhoffer N, Garcia MN, Garona J, González B, Gottardo F, Grasso D, Iovanna J, Kohan G, Lada PE, Mazza O, Monte M, Papademetrio D, Pasqualini ME, Sahores A, Santofimia P, Yaneff A. Chuluyan E, et al. Among authors: iovanna j. Medicina (B Aires). 2023;83(4):650-652. Medicina (B Aires). 2023. PMID: 37582144 Free article. Spanish. No abstract available.
Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma.
Saillard C, Delecourt F, Schmauch B, Moindrot O, Svrcek M, Bardier-Dupas A, Emile JF, Ayadi M, Rebours V, de Mestier L, Hammel P, Neuzillet C, Bachet JB, Iovanna J, Dusetti N, Blum Y, Richard M, Kermezli Y, Paradis V, Zaslavskiy M, Courtiol P, Kamoun A, Nicolle R, Cros J. Saillard C, et al. Among authors: iovanna j. Nat Commun. 2023 Jun 13;14(1):3459. doi: 10.1038/s41467-023-39026-y. Nat Commun. 2023. PMID: 37311751 Free PMC article.
Combining the antianginal drug perhexiline with chemotherapy induces complete pancreatic cancer regression in vivo.
Reyes-Castellanos G, Abdel Hadi N, Gallardo-Arriaga S, Masoud R, Garcia J, Lac S, El Kaoutari A, Gicquel T, Planque M, Fendt SM, Linares LK, Gayet O, Guillaumond F, Dusetti N, Iovanna J, Carrier A. Reyes-Castellanos G, et al. Among authors: iovanna j. iScience. 2023 May 19;26(6):106899. doi: 10.1016/j.isci.2023.106899. eCollection 2023 Jun 16. iScience. 2023. PMID: 37305702 Free PMC article.
462 results