Letter: Mass spectrometric approach of high pH- and copper-induced glutathione oxidation.
Drochioiu G, Ion L, Ciobanu C, Habasescu L, Mangalagiu I.
Drochioiu G, et al. Among authors: ion l.
Eur J Mass Spectrom (Chichester). 2013;19(1):71-5. doi: 10.1255/ejms.1210.
Eur J Mass Spectrom (Chichester). 2013.
PMID: 23841227
The interaction between copper ions and gamma-L-glutamyl-L-cysteinyl-glycine [glutathione (GSH)] molecules may lead to the formation of the physiologically occurring Cu[I)-[GSH]2 and Cu(II)-GSSG complexes. Since glutathione depletion in neurons and aberrant copper m …
The interaction between copper ions and gamma-L-glutamyl-L-cysteinyl-glycine [glutathione (GSH)] molecules may lead to the for …