Hughes LP - Search Results

1

Structural characterisation of amorphous solid dispersions via metropolis matrix factorisation of pair distribution function data.

Geddes HS, Blade H, McCabe JF, Hughes LP, Goodwin AL. Geddes HS, et al. Among authors: hughes lp. Chem Commun (Camb). 2019 Nov 18;55(89):13346-13349. doi: 10.1039/c9cc06753a. Epub 2019 Oct 3. Chem Commun (Camb). 2019. PMID: 31580357

2

Toward Developing a Predictive Approach To Assess Electron Beam Instability during Transmission Electron Microscopy of Drug Molecules.

S'ari M, Blade H, Brydson R, Cosgrove SD, Hondow N, Hughes LP, Brown A. S'ari M, et al. Among authors: hughes lp. Mol Pharm. 2018 Nov 5;15(11):5114-5123. doi: 10.1021/acs.molpharmaceut.8b00693. Epub 2018 Sep 28. Mol Pharm. 2018. PMID: 30212216 Free article.

3

5-amino-2-methylpyridinium hydrogen fumarate: An XRD and NMR crystallography analysis.

Corlett EK, Blade H, Hughes LP, Sidebottom PJ, Walker D, Walton RI, Brown SP. Corlett EK, et al. Among authors: hughes lp. Magn Reson Chem. 2020 Nov;58(11):1026-1035. doi: 10.1002/mrc.5021. Epub 2020 Mar 29. Magn Reson Chem. 2020. PMID: 32187751

4

NMR and Thermal Studies for the Characterization of Mass Transport and Phase Separation in Paracetamol/Copovidone Hot-Melt Extrusion Formulations.

Pisa E, Hughes LP, Wren SAC, Booth J, McCabe JF, Whittaker DTE, Mantle MD. Pisa E, et al. Among authors: hughes lp. Mol Pharm. 2020 Jun 1;17(6):2021-2033. doi: 10.1021/acs.molpharmaceut.0c00188. Epub 2020 Apr 27. Mol Pharm. 2020. PMID: 32298130

5

Investigating discrepancies between experimental solid-state NMR and GIPAW calculation: NC-N ¹³C and OH⋯O ¹H chemical shifts in pyridinium fumarates and their cocrystals.

Corlett EK, Blade H, Hughes LP, Sidebottom PJ, Walker D, Walton RI, Brown SP. Corlett EK, et al. Among authors: hughes lp. Solid State Nucl Magn Reson. 2020 Aug;108:101662. doi: 10.1016/j.ssnmr.2020.101662. Epub 2020 Apr 10. Solid State Nucl Magn Reson. 2020. PMID: 32590237 Free article.

6

Conformations in Solution and in Solid-State Polymorphs: Correlating Experimental and Calculated Nuclear Magnetic Resonance Chemical Shifts for Tolfenamic Acid.

Blade H, Blundell CD, Brown SP, Carson J, Dannatt HRW, Hughes LP, Menakath AK. Blade H, et al. Among authors: hughes lp. J Phys Chem A. 2020 Oct 29;124(43):8959-8977. doi: 10.1021/acs.jpca.0c07000. Epub 2020 Oct 16. J Phys Chem A. 2020. PMID: 32946236

7

A curious case of dynamic disorder in pyrrolidine rings elucidated by NMR crystallography.

Szell PMJ , Brown SP , Hughes LP , Blade H , Nilsson Lill SO . Szell PMJ , et al. Among authors: hughes lp. Chem Commun (Camb). 2020 Nov 21;56(90):14039-14042. doi: 10.1039/d0cc05236a. Epub 2020 Oct 26. Chem Commun (Camb). 2020. PMID: 33103694

8

Characterization of Amorphous Solid Dispersions and Identification of Low Levels of Crystallinity by Transmission Electron Microscopy.

S'ari M, Blade H, Cosgrove S, Drummond-Brydson R, Hondow N, Hughes LP, Brown A. S'ari M, et al. Among authors: hughes lp. Mol Pharm. 2021 May 3;18(5):1905-1919. doi: 10.1021/acs.molpharmaceut.0c00918. Epub 2021 Apr 2. Mol Pharm. 2021. PMID: 33797925 Free article.

9

A toolbox for improving the workflow of NMR crystallography.

Szell PMJ, Nilsson Lill SO, Blade H, Brown SP, Hughes LP. Szell PMJ, et al. Among authors: hughes lp. Solid State Nucl Magn Reson. 2021 Dec;116:101761. doi: 10.1016/j.ssnmr.2021.101761. Epub 2021 Oct 12. Solid State Nucl Magn Reson. 2021. PMID: 34736104

10

Combining X-ray and NMR Crystallography to Explore the Crystallographic Disorder in Salbutamol Oxalate.

Al-Ani AJ, Szell PMJ, Rehman Z, Blade H, Wheatcroft HP, Hughes LP, Brown SP, Wilson CC. Al-Ani AJ, et al. Among authors: hughes lp. Cryst Growth Des. 2022 Aug 3;22(8):4696-4707. doi: 10.1021/acs.cgd.1c01093. Epub 2022 Jul 20. Cryst Growth Des. 2022. PMID: 35971412 Free PMC article.

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