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Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites.
Jarrad AM, Karoli T, Debnath A, Tay CY, Huang JX, Kaeslin G, Elliott AG, Miyamoto Y, Ramu S, Kavanagh AM, Zuegg J, Eckmann L, Blaskovich MA, Cooper MA. Jarrad AM, et al. Among authors: huang jx. Eur J Med Chem. 2015 Aug 28;101:96-102. doi: 10.1016/j.ejmech.2015.06.019. Epub 2015 Jun 18. Eur J Med Chem. 2015. PMID: 26117821 Free PMC article.
Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B.
Gallardo-Godoy A, Muldoon C, Becker B, Elliott AG, Lash LH, Huang JX, Butler MS, Pelingon R, Kavanagh AM, Ramu S, Phetsang W, Blaskovich MA, Cooper MA. Gallardo-Godoy A, et al. Among authors: huang jx. J Med Chem. 2016 Feb 11;59(3):1068-77. doi: 10.1021/acs.jmedchem.5b01593. Epub 2016 Jan 27. J Med Chem. 2016. PMID: 26734854 Free PMC article.
Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria.
Blaskovich MAT, Hansford KA, Gong Y, Butler MS, Muldoon C, Huang JX, Ramu S, Silva AB, Cheng M, Kavanagh AM, Ziora Z, Premraj R, Lindahl F, Bradford TA, Lee JC, Karoli T, Pelingon R, Edwards DJ, Amado M, Elliott AG, Phetsang W, Daud NH, Deecke JE, Sidjabat HE, Ramaologa S, Zuegg J, Betley JR, Beevers APG, Smith RAG, Roberts JA, Paterson DL, Cooper MA. Blaskovich MAT, et al. Among authors: huang jx. Nat Commun. 2018 Jan 2;9(1):22. doi: 10.1038/s41467-017-02123-w. Nat Commun. 2018. PMID: 29295973 Free PMC article.
Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.
Velkov T, Gallardo-Godoy A, Swarbrick JD, Blaskovich MAT, Elliott AG, Han M, Thompson PE, Roberts KD, Huang JX, Becker B, Butler MS, Lash LH, Henriques ST, Nation RL, Sivanesan S, Sani MA, Separovic F, Mertens H, Bulach D, Seemann T, Owen J, Li J, Cooper MA. Velkov T, et al. Among authors: huang jx. Cell Chem Biol. 2018 Apr 19;25(4):380-391.e5. doi: 10.1016/j.chembiol.2018.01.005. Epub 2018 Feb 3. Cell Chem Biol. 2018. PMID: 29396290 Free PMC article.
Structure-Function Studies of Polymyxin B Lipononapeptides.
Gallardo-Godoy A, Hansford KA, Muldoon C, Becker B, Elliott AG, Huang JX, Pelingon R, Butler MS, Blaskovich MAT, Cooper MA. Gallardo-Godoy A, et al. Among authors: huang jx. Molecules. 2019 Feb 2;24(3):553. doi: 10.3390/molecules24030553. Molecules. 2019. PMID: 30717415 Free PMC article.
Mucin Binding Reduces Colistin Antimicrobial Activity.
Huang JX, Blaskovich MA, Pelingon R, Ramu S, Kavanagh A, Elliott AG, Butler MS, Montgomery AB, Cooper MA. Huang JX, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):5925-31. doi: 10.1128/AAC.00808-15. Epub 2015 Jul 13. Antimicrob Agents Chemother. 2015. PMID: 26169405 Free PMC article.
429 results