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The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles.
Leidal AM, Huang HH, Marsh T, Solvik T, Zhang D, Ye J, Kai F, Goldsmith J, Liu JY, Huang YH, Monkkonen T, Vlahakis A, Huang EJ, Goodarzi H, Yu L, Wiita AP, Debnath J. Leidal AM, et al. Among authors: huang yh, huang hh, huang ej. Nat Cell Biol. 2020 Feb;22(2):187-199. doi: 10.1038/s41556-019-0450-y. Epub 2020 Jan 13. Nat Cell Biol. 2020. PMID: 31932738 Free PMC article.
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, Farese RV Jr, Taylor JP, Ullian EM, Huang B, Debnath J, Wittmann T, Kriegstein AR, Huang EJ. Zhang J, et al. Among authors: huang yh, huang b, huang ej. Nature. 2020 Dec;588(7838):459-465. doi: 10.1038/s41586-020-2709-7. Epub 2020 Aug 31. Nature. 2020. PMID: 32866962 Free PMC article.
Label-retention expansion microscopy.
Shi X, Li Q, Dai Z, Tran AA, Feng S, Ramirez AD, Lin Z, Wang X, Chow TT, Chen J, Kumar D, McColloch AR, Reiter JF, Huang EJ, Seiple IB, Huang B. Shi X, et al. Among authors: huang b, huang ej. J Cell Biol. 2021 Sep 6;220(9):e202105067. doi: 10.1083/jcb.202105067. Epub 2021 Jul 6. J Cell Biol. 2021. PMID: 34228783 Free PMC article.
Secretory autophagy maintains proteostasis upon lysosome inhibition.
Solvik TA, Nguyen TA, Tony Lin YH, Marsh T, Huang EJ, Wiita AP, Debnath J, Leidal AM. Solvik TA, et al. Among authors: huang ej. J Cell Biol. 2022 Jun 6;221(6):e202110151. doi: 10.1083/jcb.202110151. Epub 2022 Apr 21. J Cell Biol. 2022. PMID: 35446347 Free PMC article.
212 results