Howell AR - Search Results

1

Chemical proteomic analysis of palmostatin beta-lactone analogs that affect N-Ras palmitoylation.

Suciu RM, Luvaga IK, Hazeen A, Weerasooriya C, Richardson SK, Firestone AJ, Shannon K, Howell AR, Cravatt BF. Suciu RM, et al. Among authors: howell ar. Bioorg Med Chem Lett. 2021 Dec 1;53:128414. doi: 10.1016/j.bmcl.2021.128414. Epub 2021 Oct 16. Bioorg Med Chem Lett. 2021. PMID: 34666187 Free PMC article.

2

Straightforward synthesis of sphinganines via a serine-derived Weinreb amide.

So RC, Ndonye R, Izmirian DP, Richardson SK, Guerrera RL, Howell AR. So RC, et al. Among authors: howell ar. J Org Chem. 2004 Apr 30;69(9):3233-5. doi: 10.1021/jo030355b. J Org Chem. 2004. PMID: 15104474

3

The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.

Sidobre S, Hammond KJ, Bénazet-Sidobre L, Maltsev SD, Richardson SK, Ndonye RM, Howell AR, Sakai T, Besra GS, Porcelli SA, Kronenberg M. Sidobre S, et al. Among authors: howell ar. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12254-9. doi: 10.1073/pnas.0404632101. Epub 2004 Aug 10. Proc Natl Acad Sci U S A. 2004. PMID: 15304644 Free PMC article.

4

Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH.

Ndonye RM, Izmirian DP, Dunn MF, Yu KO, Porcelli SA, Khurana A, Kronenberg M, Richardson SK, Howell AR. Ndonye RM, et al. Among authors: howell ar. J Org Chem. 2005 Dec 9;70(25):10260-70. doi: 10.1021/jo051147h. J Org Chem. 2005. PMID: 16323834

5

Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells.

Kinjo Y, Pei B, Bufali S, Raju R, Richardson SK, Imamura M, Fujio M, Wu D, Khurana A, Kawahara K, Wong CH, Howell AR, Seeberger PH, Kronenberg M. Kinjo Y, et al. Among authors: howell ar. Chem Biol. 2008 Jul 21;15(7):654-64. doi: 10.1016/j.chembiol.2008.05.012. Chem Biol. 2008. PMID: 18635002 Free PMC article.

6

Synthesis and evaluation of 3''- and 4''-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000.

Raju R, Castillo BF, Richardson SK, Thakur M, Severins R, Kronenberg M, Howell AR. Raju R, et al. Among authors: howell ar. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4122-5. doi: 10.1016/j.bmcl.2009.06.005. Epub 2009 Jun 6. Bioorg Med Chem Lett. 2009. PMID: 19535248 Free PMC article.

7

Cloning and characterization of a hybridoma secreting a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-specific monoclonal antibody and recombinant F(ab).

Wanczyk H, Barker T, Rood D, Zapata DI, Howell AR, Richardson SK, Zinckgraf J, Marusov GP, Lynes MA, Silbart LK. Wanczyk H, et al. Among authors: howell ar. Toxins (Basel). 2013 Mar 19;5(3):568-89. doi: 10.3390/toxins5030568. Toxins (Basel). 2013. PMID: 23518474 Free PMC article.

8

Combining cross-metathesis and activity-based protein profiling: new β-lactone motifs for targeting serine hydrolases.

Camara K, Kamat SS, Lasota CC, Cravatt BF, Howell AR. Camara K, et al. Among authors: howell ar. Bioorg Med Chem Lett. 2015 Jan 15;25(2):317-21. doi: 10.1016/j.bmcl.2014.11.038. Bioorg Med Chem Lett. 2015. PMID: 25541002 Free PMC article.

9

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay.

Kamat SS, Camara K, Parsons WH, Chen DH, Dix MM, Bird TD, Howell AR, Cravatt BF. Kamat SS, et al. Among authors: howell ar. Nat Chem Biol. 2015 Feb;11(2):164-71. doi: 10.1038/nchembio.1721. Epub 2015 Jan 12. Nat Chem Biol. 2015. PMID: 25580854 Free PMC article.

10

1,4-Dicarbofunctionalization of 4-Fluoroaryl Grignard and Lithium Reagents with Disubstituted Malononitriles.

Malapit CA, Luvaga IK, Reeves JT, Volchkov I, Busacca CA, Howell AR, Senanayake CH. Malapit CA, et al. Among authors: howell ar. J Org Chem. 2017 May 5;82(9):4993-4997. doi: 10.1021/acs.joc.7b00567. Epub 2017 Apr 14. J Org Chem. 2017. PMID: 28402664

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