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Taxol®: The First Microtubule Stabilizing Agent.
Yang CH, Horwitz SB. Yang CH, et al. Among authors: horwitz sb. Int J Mol Sci. 2017 Aug 9;18(8):1733. doi: 10.3390/ijms18081733. Int J Mol Sci. 2017. PMID: 28792473 Free PMC article. Review.
Structural Basis of Microtubule Stabilization by Discodermolide.
Prota AE, Bargsten K, Redondo-Horcajo M, Smith AB 3rd, Yang CH, McDaid HM, Paterson I, Horwitz SB, Fernando Díaz J, Steinmetz MO. Prota AE, et al. Among authors: horwitz sb. Chembiochem. 2017 May 18;18(10):905-909. doi: 10.1002/cbic.201600696. Epub 2017 Mar 27. Chembiochem. 2017. PMID: 28207984 Free PMC article.
Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes.
Doodhi H, Prota AE, Rodríguez-García R, Xiao H, Custar DW, Bargsten K, Katrukha EA, Hilbert M, Hua S, Jiang K, Grigoriev I, Yang CH, Cox D, Horwitz SB, Kapitein LC, Akhmanova A, Steinmetz MO. Doodhi H, et al. Among authors: horwitz sb. Curr Biol. 2016 Jul 11;26(13):1713-1721. doi: 10.1016/j.cub.2016.04.053. Epub 2016 Jun 16. Curr Biol. 2016. PMID: 27321995 Free article.
Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners.
Nadaradjane C, Yang CH, Rodriguez-Gabin A, Ye K, Sugasawa K, Atasoylu O, Smith AB 3rd, Horwitz SB, McDaid HM. Nadaradjane C, et al. Among authors: horwitz sb. J Nat Prod. 2018 Mar 23;81(3):607-615. doi: 10.1021/acs.jnatprod.8b00111. Epub 2018 Mar 9. J Nat Prod. 2018. PMID: 29522336 Free PMC article.
Insights into the mechanism of microtubule stabilization by Taxol.
Xiao H, Verdier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB, Orr GA. Xiao H, et al. Among authors: horwitz sb. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10166-10173. doi: 10.1073/pnas.0603704103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801540 Free PMC article.
224 results