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Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs.
Ulrichts H, Silence K, Schoolmeester A, de Jaegere P, Rossenu S, Roodt J, Priem S, Lauwereys M, Casteels P, Van Bockstaele F, Verschueren K, Stanssens P, Baumeister J, Holz JB. Ulrichts H, et al. Among authors: holz jb. Blood. 2011 Jul 21;118(3):757-65. doi: 10.1182/blood-2010-11-317859. Epub 2011 May 16. Blood. 2011. PMID: 21576702 Free article.
Relation of endothelial function to residual platelet reactivity after clopidogrel in patients with stable angina pectoris undergoing percutaneous coronary intervention.
Muller O, Hamilos M, Bartunek J, Ulrichts H, Mangiacapra F, Holz JB, Ntalianis A, Trana C, Dierickx K, Vercruysse K, De Bruyne B, Wijns W, Barbato E. Muller O, et al. Among authors: holz jb. Am J Cardiol. 2010 Feb 1;105(3):333-8. doi: 10.1016/j.amjcard.2009.09.033. Epub 2009 Dec 22. Am J Cardiol. 2010. PMID: 20102944
von Willebrand factor inhibition improves endothelial function in patients with stable angina.
Muller O, Bartunek J, Hamilos M, Berza CT, Mangiacapra F, Ntalianis A, Vercruysse K, Duby C, Wijns W, De Bruyne B, Heyndrickx GR, Vanderheyden M, Holz JB, Barbato E. Muller O, et al. Among authors: holz jb. J Cardiovasc Transl Res. 2013 Jun;6(3):364-70. doi: 10.1007/s12265-012-9422-3. Epub 2012 Dec 12. J Cardiovasc Transl Res. 2013. PMID: 23233321 Clinical Trial.
A Phase 1 First-in-Human Study of FS118, a Tetravalent Bispecific Antibody Targeting LAG-3 and PD-L1 in Patients with Advanced Cancer and PD-L1 Resistance.
Yap TA, LoRusso PM, Wong DJ, Hu-Lieskovan S, Papadopoulos KP, Holz JB, Grabowska U, Gradinaru C, Leung KM, Marshall S, Reader CS, Russell R, Sainson RCA, Seal CJ, Shepherd CJ, Germaschewski F, Gliddon D, Stern O, Young L, Brewis N, Kayitalire L, Morrow M. Yap TA, et al. Among authors: holz jb. Clin Cancer Res. 2023 Mar 1;29(5):888-898. doi: 10.1158/1078-0432.CCR-22-1449. Clin Cancer Res. 2023. PMID: 36342102
12 results