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Chemoselective Wittig and Michael ligations of unprotected peptidyl phosphoranes in water furnish potent inhibitors of caspase-3.
Org Lett. 2014 Sep 5;16(17):4428-31. doi: 10.1021/ol501910x. Epub 2014 Aug 20.
Org Lett. 2014.
PMID: 25141292
Maintaining biological activity by using triazoles as disulfide bond mimetics.
Holland-Nell K, Meldal M.
Holland-Nell K, et al.
Angew Chem Int Ed Engl. 2011 May 23;50(22):5204-6. doi: 10.1002/anie.201005846. Epub 2011 Mar 29.
Angew Chem Int Ed Engl. 2011.
PMID: 21472909
No abstract available.
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Simultaneous "one pot" expressed protein ligation and CuI-catalyzed azide/alkyne cycloaddition for protein immobilization.
Steinhagen M, Holland-Nell K, Meldal M, Beck-Sickinger AG.
Steinhagen M, et al. Among authors: holland nell k.
Chembiochem. 2011 Nov 4;12(16):2426-30. doi: 10.1002/cbic.201100434. Epub 2011 Sep 8.
Chembiochem. 2011.
PMID: 21901810
No abstract available.
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Specifically immobilised aldo/keto reductase AKR1A1 shows a dramatic increase in activity relative to the randomly immobilised enzyme.
Holland-Nell K, Beck-Sickinger AG.
Holland-Nell K, et al.
Chembiochem. 2007 Jun 18;8(9):1071-6. doi: 10.1002/cbic.200700056.
Chembiochem. 2007.
PMID: 17508367
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Cluster properties of peptides on (100) semiconductor surfaces.
Goede K, Grundmann M, Holland-Nell K, Beck-Sickinger AG.
Goede K, et al. Among authors: holland nell k.
Langmuir. 2006 Sep 12;22(19):8104-8. doi: 10.1021/la0605236.
Langmuir. 2006.
PMID: 16952248
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Mapping of phosphorylation-dependent anti-tau monoclonal antibodies in immunoblots using human tau-constructs synthesized by native chemical ligation.
Singer D, Herth N, Kuhlmann J, Holland-Nell K, Beck-Sickinger AG, Hoffmann R.
Singer D, et al. Among authors: holland nell k.
Biochem Biophys Res Commun. 2008 Mar 7;367(2):318-22. doi: 10.1016/j.bbrc.2007.12.109. Epub 2007 Dec 26.
Biochem Biophys Res Commun. 2008.
PMID: 18162172
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