Hoke DE - Search Results

1

Potent, multi-target serine protease inhibition achieved by a simplified β-sheet motif.

Chen X, Riley BT, de Veer SJ, Hoke DE, Van Haeften J, Leahy D, Swedberg JE, Brattsand M, Hartfield PJ, Buckle AM, Harris JM. Chen X, et al. Among authors: hoke de. PLoS One. 2019 Jan 22;14(1):e0210842. doi: 10.1371/journal.pone.0210842. eCollection 2019. PLoS One. 2019. PMID: 30668585 Free PMC article.

2

Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics.

Riley BT, Ilyichova O, Costa MG, Porebski BT, de Veer SJ, Swedberg JE, Kass I, Harris JM, Hoke DE, Buckle AM. Riley BT, et al. Among authors: hoke de. Sci Rep. 2016 Oct 21;6:35385. doi: 10.1038/srep35385. Sci Rep. 2016. PMID: 27767076 Free PMC article.

3

KLK4 Inhibition by Cyclic and Acyclic Peptides: Structural and Dynamical Insights into Standard-Mechanism Protease Inhibitors.

Riley BT, Ilyichova O, de Veer SJ, Swedberg JE, Wilson E, Hoke DE, Harris JM, Buckle AM. Riley BT, et al. Among authors: hoke de. Biochemistry. 2019 May 28;58(21):2524-2533. doi: 10.1021/acs.biochem.9b00191. Epub 2019 May 13. Biochemistry. 2019. PMID: 31058493

4

Crystal structure of the inhibitor-free form of the serine protease kallikrein-4.

Riley BT, Hoke DE, McGowan S, Buckle AM. Riley BT, et al. Among authors: hoke de. Acta Crystallogr F Struct Biol Commun. 2019 Aug 1;75(Pt 8):543-546. doi: 10.1107/S2053230X19009610. Epub 2019 Jul 16. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 31397325 Free PMC article.

5

Modelling of Thyroid Peroxidase Reveals Insights into Its Enzyme Function and Autoantigenicity.

Le SN, Porebski BT, McCoey J, Fodor J, Riley B, Godlewska M, Góra M, Czarnocka B, Banga JP, Hoke DE, Kass I, Buckle AM. Le SN, et al. Among authors: hoke de. PLoS One. 2015 Dec 1;10(12):e0142615. doi: 10.1371/journal.pone.0142615. eCollection 2015. PLoS One. 2015. PMID: 26623656 Free PMC article.

6

Reactive centre loop dynamics and serpin specificity.

Marijanovic EM, Fodor J, Riley BT, Porebski BT, Costa MGS, Kass I, Hoke DE, McGowan S, Buckle AM. Marijanovic EM, et al. Among authors: hoke de. Sci Rep. 2019 Mar 7;9(1):3870. doi: 10.1038/s41598-019-40432-w. Sci Rep. 2019. PMID: 30846766 Free PMC article.

7

Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain.

Porebski BT, Nickson AA, Hoke DE, Hunter MR, Zhu L, McGowan S, Webb GI, Buckle AM. Porebski BT, et al. Among authors: hoke de. Protein Eng Des Sel. 2015 Mar;28(3):67-78. doi: 10.1093/protein/gzv002. Protein Eng Des Sel. 2015. PMID: 25691761 Free PMC article.

8

An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes.

Jayakrishnan B, Hoke DE, Langendorf CG, Buckle AM, Rowley MJ. Jayakrishnan B, et al. Among authors: hoke de. PLoS One. 2011 Apr 8;6(4):e18411. doi: 10.1371/journal.pone.0018411. PLoS One. 2011. PMID: 21494613 Free PMC article.

9

Thyroid Peroxidase as an Autoantigen in Hashimoto's Disease: Structure, Function, and Antigenicity.

Williams DE, Le SN, Godlewska M, Hoke DE, Buckle AM. Williams DE, et al. Among authors: hoke de. Horm Metab Res. 2018 Dec;50(12):908-921. doi: 10.1055/a-0717-5514. Epub 2018 Oct 25. Horm Metab Res. 2018. PMID: 30360003 Review.

10

Circumventing the stability-function trade-off in an engineered FN3 domain.

Porebski BT, Conroy PJ, Drinkwater N, Schofield P, Vazquez-Lombardi R, Hunter MR, Hoke DE, Christ D, McGowan S, Buckle AM. Porebski BT, et al. Among authors: hoke de. Protein Eng Des Sel. 2016 Nov 1;29(11):541-550. doi: 10.1093/protein/gzw046. Protein Eng Des Sel. 2016. PMID: 27578887 Free PMC article.

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