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Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Badgley MA, Kremer DM, Maurer HC, DelGiorno KE, Lee HJ, Purohit V, Sagalovskiy IR, Ma A, Kapilian J, Firl CEM, Decker AR, Sastra SA, Palermo CF, Andrade LR, Sajjakulnukit P, Zhang L, Tolstyka ZP, Hirschhorn T, Lamb C, Liu T, Gu W, Seeley ES, Stone E, Georgiou G, Manor U, Iuga A, Wahl GM, Stockwell BR, Lyssiotis CA, Olive KP. Badgley MA, et al. Among authors: hirschhorn t. Science. 2020 Apr 3;368(6486):85-89. doi: 10.1126/science.aaw9872. Science. 2020. PMID: 32241947 Free PMC article.
The development of the concept of ferroptosis.
Hirschhorn T, Stockwell BR. Hirschhorn T, et al. Free Radic Biol Med. 2019 Mar;133:130-143. doi: 10.1016/j.freeradbiomed.2018.09.043. Epub 2018 Sep 28. Free Radic Biol Med. 2019. PMID: 30268886 Free PMC article. Review.
Vitamin K: A new guardian against ferroptosis.
Hirschhorn T, Stockwell BR. Hirschhorn T, et al. Mol Cell. 2022 Oct 20;82(20):3760-3762. doi: 10.1016/j.molcel.2022.10.001. Mol Cell. 2022. PMID: 36270246 Free article.
Identification of essential sites of lipid peroxidation in ferroptosis.
von Krusenstiern AN, Robson RN, Qian N, Qiu B, Hu F, Reznik E, Smith N, Zandkarimi F, Estes VM, Dupont M, Hirschhorn T, Shchepinov MS, Min W, Woerpel KA, Stockwell BR. von Krusenstiern AN, et al. Among authors: hirschhorn t. Nat Chem Biol. 2023 Jun;19(6):719-730. doi: 10.1038/s41589-022-01249-3. Epub 2023 Feb 6. Nat Chem Biol. 2023. PMID: 36747055 Free PMC article.
Ferroptosis inhibition by oleic acid mitigates iron-overload-induced injury.
Mann J, Reznik E, Santer M, Fongheiser MA, Smith N, Hirschhorn T, Zandkarimi F, Soni RK, Dafré AL, Miranda-Vizuete A, Farina M, Stockwell BR. Mann J, et al. Among authors: hirschhorn t. Cell Chem Biol. 2024 Feb 15;31(2):249-264.e7. doi: 10.1016/j.chembiol.2023.10.012. Epub 2023 Nov 8. Cell Chem Biol. 2024. PMID: 37944523
Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-β.
Shapira KE, Hirschhorn T, Barzilay L, Smorodinsky NI, Henis YI, Ehrlich M. Shapira KE, et al. Among authors: hirschhorn t. Mol Biol Cell. 2014 May;25(10):1620-8. doi: 10.1091/mbc.E13-09-0537. Epub 2014 Mar 19. Mol Biol Cell. 2014. PMID: 24648493 Free PMC article.
15 results