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Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Panicker N, Kam TI, Wang H, Neifert S, Chou SC, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, Mao X, Xu E, Karuppagounder SS, Hsu ET, Kang SU, Pletnikova O, Troncoso J, Dawson VL, Dawson TM. Panicker N, et al. Among authors: hinkle jt. Neuron. 2022 Aug 3;110(15):2422-2437.e9. doi: 10.1016/j.neuron.2022.05.009. Epub 2022 Jun 1. Neuron. 2022. PMID: 35654037 Free PMC article.
Domain-specific cognitive impairment in non-demented Parkinson's disease psychosis.
Hinkle JT, Perepezko K, Bakker CC, Dawson TM, Johnson V, Mari Z, Marvel CL, Mills KA, Pantelyat A, Pletnikova O, Rosenthal LS, Shepard MD, Stevens DA, Troncoso JC, Wang J, Pontone GM. Hinkle JT, et al. Int J Geriatr Psychiatry. 2018 Jan;33(1):e131-e139. doi: 10.1002/gps.4736. Epub 2017 May 16. Int J Geriatr Psychiatry. 2018. PMID: 28509347 Free PMC article.
Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias.
Hinkle JT, Perepezko K, Rosenthal LS, Mills KA, Pantelyat A, Mari Z, Tochen L, Bang JY, Gudavalli M, Yoritomo N, Butala A, Bakker CC, Johnson V, Moukheiber E, Dawson TM, Pontone GM. Hinkle JT, et al. Parkinsonism Relat Disord. 2018 Feb;47:50-56. doi: 10.1016/j.parkreldis.2017.11.338. Epub 2017 Nov 21. Parkinsonism Relat Disord. 2018. PMID: 29198499 Free PMC article.
Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias.
Hinkle JT, Perepezko K, Rosenthal LS, Mills KA, Pantelyat A, Mari Z, Butala A, Moukheiber E, Dawson TM, Pontone GM. Hinkle JT, et al. Parkinsonism Relat Disord. 2018 Aug;53:108-109. doi: 10.1016/j.parkreldis.2018.04.027. Epub 2018 May 2. Parkinsonism Relat Disord. 2018. PMID: 29753604 No abstract available.
Onset and Remission of Psychosis in Parkinson's Disease: Pharmacologic and Motoric Markers.
Hinkle JT, Perepezko K, Bakker CC, Broen MPG, Chin K, Dawson TM, Johnson V, Mari Z, Marvel CL, Mills KA, Pantelyat A, Pletnikova O, Rosenthal LS, Shepard MD, Stevens DA, Troncoso JC, Wang J, Pontone GM. Hinkle JT, et al. Mov Disord Clin Pract. 2018 Jan-Feb;5(1):31-38. doi: 10.1002/mdc3.12550. Epub 2017 Sep 15. Mov Disord Clin Pract. 2018. PMID: 29756003 Free PMC article.
Microglia and astrocyte dysfunction in parkinson's disease.
Kam TI, Hinkle JT, Dawson TM, Dawson VL. Kam TI, et al. Among authors: hinkle jt. Neurobiol Dis. 2020 Oct;144:105028. doi: 10.1016/j.nbd.2020.105028. Epub 2020 Jul 28. Neurobiol Dis. 2020. PMID: 32736085 Free PMC article. Review.
Brainstem Pathologies Correlate With Depression and Psychosis in Parkinson's Disease.
Fischer NM, Hinkle JT, Perepezko K, Bakker CC, Morris M, Broen MPG, Butala A, Dawson TM, Leentjens AFG, Mari Z, Marvel CL, Mills KA, Rosenthal LS, Shepard MD, Pantelyat A, Bakker A, Pletnikova O, Troncoso JC, Wang J, Pontone GM. Fischer NM, et al. Among authors: hinkle jt. Am J Geriatr Psychiatry. 2021 Sep;29(9):958-968. doi: 10.1016/j.jagp.2020.12.009. Epub 2021 Jan 15. Am J Geriatr Psychiatry. 2021. PMID: 33455856 Free PMC article.
STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Hinkle JT, Patel J, Panicker N, Karuppagounder SS, Biswas D, Belingon B, Chen R, Brahmachari S, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM. Hinkle JT, et al. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2118819119. doi: 10.1073/pnas.2118819119. Epub 2022 Apr 8. Proc Natl Acad Sci U S A. 2022. PMID: 35394877 Free PMC article.
36 results