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Critical functions of N6-adenosine methylation of mRNAs in T cells.
Ito-Kureha T, Heissmeyer V. Ito-Kureha T, et al. Among authors: heissmeyer v. Biochim Biophys Acta Mol Cell Res. 2023 Jan;1870(1):119380. doi: 10.1016/j.bbamcr.2022.119380. Epub 2022 Oct 11. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 36228837 Free article. Review.
Validation strategies for antibodies targeting modified ribonucleotides.
Weichmann F, Hett R, Schepers A, Ito-Kureha T, Flatley A, Slama K, Hastert FD, Angstman NB, Cardoso MC, König J, Hüttelmaier S, Dieterich C, Canzar S, Helm M, Heissmeyer V, Feederle R, Meister G. Weichmann F, et al. Among authors: heissmeyer v. RNA. 2020 Oct;26(10):1489-1506. doi: 10.1261/rna.076026.120. Epub 2020 Jul 7. RNA. 2020. PMID: 32636310 Free PMC article.
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
Hoefig KP, Reim A, Gallus C, Wong EH, Behrens G, Conrad C, Xu M, Kifinger L, Ito-Kureha T, Defourny KAY, Geerlof A, Mautner J, Hauck SM, Baumjohann D, Feederle R, Mann M, Wierer M, Glasmacher E, Heissmeyer V. Hoefig KP, et al. Among authors: heissmeyer v. Nat Commun. 2021 Sep 1;12(1):5208. doi: 10.1038/s41467-021-25345-5. Nat Commun. 2021. PMID: 34471108 Free PMC article.
The function of Wtap in N6-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells.
Ito-Kureha T, Leoni C, Borland K, Cantini G, Bataclan M, Metzger RN, Ammann G, Krug AB, Marsico A, Kaiser S, Canzar S, Feske S, Monticelli S, König J, Heissmeyer V. Ito-Kureha T, et al. Among authors: heissmeyer v. Nat Immunol. 2022 Aug;23(8):1208-1221. doi: 10.1038/s41590-022-01268-1. Epub 2022 Jul 25. Nat Immunol. 2022. PMID: 35879451
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
Xu M, Ito-Kureha T, Kang HS, Chernev A, Raj T, Hoefig KP, Hohn C, Giesert F, Wang Y, Pan W, Ziętara N, Straub T, Feederle R, Daniel C, Adler B, König J, Feske S, Tsokos GC, Wurst W, Urlaub H, Sattler M, Kisielow J, Wulczyn FG, Łyszkiewicz M, Heissmeyer V. Xu M, et al. Among authors: heissmeyer v. Nat Commun. 2024 Mar 11;15(1):2194. doi: 10.1038/s41467-024-46371-z. Nat Commun. 2024. PMID: 38467629 Free PMC article.
Posttranscriptional regulation of T helper cell fate decisions.
Hoefig KP, Heissmeyer V. Hoefig KP, et al. Among authors: heissmeyer v. J Cell Biol. 2018 Aug 6;217(8):2615-2631. doi: 10.1083/jcb.201708075. Epub 2018 Apr 23. J Cell Biol. 2018. PMID: 29685903 Free PMC article. Review.
Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation.
Vogel KU, Edelmann SL, Jeltsch KM, Bertossi A, Heger K, Heinz GA, Zöller J, Warth SC, Hoefig KP, Lohs C, Neff F, Kremmer E, Schick J, Repsilber D, Geerlof A, Blum H, Wurst W, Heikenwälder M, Schmidt-Supprian M, Heissmeyer V. Vogel KU, et al. Among authors: heissmeyer v. Immunity. 2013 Apr 18;38(4):655-68. doi: 10.1016/j.immuni.2012.12.004. Epub 2013 Apr 11. Immunity. 2013. PMID: 23583643 Free article.
76 results