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Lymphatic vessel insufficiency in hypercholesterolemic mice alters lipoprotein levels and promotes atherogenesis.
Vuorio T, Nurmi H, Moulton K, Kurkipuro J, Robciuc MR, Ohman M, Heinonen SE, Samaranayake H, Heikura T, Alitalo K, Ylä-Herttuala S. Vuorio T, et al. Among authors: heikura t. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1162-70. doi: 10.1161/ATVBAHA.114.302528. Epub 2014 Apr 10. Arterioscler Thromb Vasc Biol. 2014. PMID: 24723556 Free PMC article.
Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.
Tuppurainen L, Sallinen H, Kokki E, Koponen J, Anttila M, Pulkkinen K, Heikura T, Toivanen P, Hämäläinen K, Kosma VM, Heinonen S, Alitalo K, Ylä-Herttuala S. Tuppurainen L, et al. Among authors: heikura t. Hum Gene Ther Clin Dev. 2013 Mar;24(1):29-37. doi: 10.1089/humc.2013.006. Epub 2013 Apr 3. Hum Gene Ther Clin Dev. 2013. PMID: 23692381
Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo.
Levonen AL, Inkala M, Heikura T, Jauhiainen S, Jyrkkänen HK, Kansanen E, Määttä K, Romppanen E, Turunen P, Rutanen J, Ylä-Herttuala S. Levonen AL, et al. Among authors: heikura t. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):741-7. doi: 10.1161/01.ATV.0000258868.80079.4d. Epub 2007 Jan 25. Arterioscler Thromb Vasc Biol. 2007. PMID: 17255530
Vascular endothelial growth factor-B induces myocardium-specific angiogenesis and arteriogenesis via vascular endothelial growth factor receptor-1- and neuropilin receptor-1-dependent mechanisms.
Lähteenvuo JE, Lähteenvuo MT, Kivelä A, Rosenlew C, Falkevall A, Klar J, Heikura T, Rissanen TT, Vähäkangas E, Korpisalo P, Enholm B, Carmeliet P, Alitalo K, Eriksson U, Ylä-Herttuala S. Lähteenvuo JE, et al. Among authors: heikura t. Circulation. 2009 Feb 17;119(6):845-56. doi: 10.1161/CIRCULATIONAHA.108.816454. Epub 2009 Feb 2. Circulation. 2009. PMID: 19188502
46 results