Heddle JG - Search Results

1

Inhibitory Compounds Targeting Plasmodium falciparum Gyrase B.

Pakosz Z, Lin TY, Michalczyk E, Nagano S, Heddle JG. Pakosz Z, et al. Among authors: heddle jg. Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0026721. doi: 10.1128/AAC.00267-21. Epub 2021 Aug 2. Antimicrob Agents Chemother. 2021. PMID: 34339271 Free PMC article.

2

Quinolone-binding pocket of DNA gyrase: role of GyrB.

Heddle J, Maxwell A. Heddle J, et al. Antimicrob Agents Chemother. 2002 Jun;46(6):1805-15. doi: 10.1128/AAC.46.6.1805-1815.2002. Antimicrob Agents Chemother. 2002. PMID: 12019094 Free PMC article.

3

Unique features of apicoplast DNA gyrases from Toxoplasma gondii and Plasmodium falciparum.

Nagano S, Lin TY, Edula JR, Heddle JG. Nagano S, et al. Among authors: heddle jg. BMC Bioinformatics. 2014 Dec 19;15(1):416. doi: 10.1186/s12859-014-0416-9. BMC Bioinformatics. 2014. PMID: 25523502 Free PMC article.

4

Investigating the Roles of the C-Terminal Domain of Plasmodium falciparum GyrA.

Nagano S, Seki E, Lin TY, Shirouzu M, Yokoyama S, Heddle JG. Nagano S, et al. Among authors: heddle jg. PLoS One. 2015 Nov 13;10(11):e0142313. doi: 10.1371/journal.pone.0142313. eCollection 2015. PLoS One. 2015. PMID: 26566222 Free PMC article.

5

A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly.

Godonoga M, Lin TY, Oshima A, Sumitomo K, Tang MSL, Cheung YW, Kinghorn AB, Dirkzwager RM, Zhou C, Kuzuya A, Tanner JA, Heddle JG. Godonoga M, et al. Among authors: heddle jg. Sci Rep. 2016 Feb 19;6:21266. doi: 10.1038/srep21266. Sci Rep. 2016. PMID: 26891622 Free PMC article.

6

Pentapeptide repeat protein QnrB1 requires ATP hydrolysis to rejuvenate poisoned gyrase complexes.

Mazurek Ł, Ghilarov D, Michalczyk E, Pakosz Z, Metelev M, Czyszczoń W, Wawro K, Behroz I, Dubiley S, Süssmuth RD, Heddle JG. Mazurek Ł, et al. Among authors: heddle jg. Nucleic Acids Res. 2021 Feb 22;49(3):1581-1596. doi: 10.1093/nar/gkaa1266. Nucleic Acids Res. 2021. PMID: 33434265 Free PMC article.

7

Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides.

Ghilarov D, Inaba-Inoue S, Stepien P, Qu F, Michalczyk E, Pakosz Z, Nomura N, Ogasawara S, Walker GC, Rebuffat S, Iwata S, Heddle JG, Beis K. Ghilarov D, et al. Among authors: heddle jg. Sci Adv. 2021 Sep 10;7(37):eabj5363. doi: 10.1126/sciadv.abj5363. Epub 2021 Sep 8. Sci Adv. 2021. PMID: 34516884 Free PMC article.

8

Enzyme encapsulation by protein cages.

Chakraborti S, Lin TY, Glatt S, Heddle JG. Chakraborti S, et al. Among authors: heddle jg. RSC Adv. 2020 Apr 1;10(22):13293-13301. doi: 10.1039/c9ra10983h. eCollection 2020 Mar 30. RSC Adv. 2020. PMID: 35492120 Free PMC article. Review.

9

Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin.

Michalczyk E, Hommernick K, Behroz I, Kulike M, Pakosz-Stępień Z, Mazurek L, Seidel M, Kunert M, Santos K, von Moeller H, Loll B, Weston JB, Mainz A, Heddle JG, Süssmuth RD, Ghilarov D. Michalczyk E, et al. Among authors: heddle jg. Nat Catal. 2023;6(1):52-67. doi: 10.1038/s41929-022-00904-1. Epub 2023 Jan 23. Nat Catal. 2023. PMID: 36741192 Free PMC article.

10

An aptamer-enabled DNA nanobox for protein sensing.

Tang MSL, Shiu SC, Godonoga M, Cheung YW, Liang S, Dirkzwager RM, Kinghorn AB, Fraser LA, Heddle JG, Tanner JA. Tang MSL, et al. Among authors: heddle jg. Nanomedicine. 2018 Jun;14(4):1161-1168. doi: 10.1016/j.nano.2018.01.018. Epub 2018 Feb 1. Nanomedicine. 2018. PMID: 29410111

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