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Molecular basis for the antiparasitic activity of a mercaptoacetamide derivative that inhibits histone deacetylase 8 (HDAC8) from the human pathogen schistosoma mansoni.
Stolfa DA, Marek M, Lancelot J, Hauser AT, Walter A, Leproult E, Melesina J, Rumpf T, Wurtz JM, Cavarelli J, Sippl W, Pierce RJ, Romier C, Jung M. Stolfa DA, et al. Among authors: hauser at. J Mol Biol. 2014 Oct 9;426(20):3442-53. doi: 10.1016/j.jmb.2014.03.007. Epub 2014 Mar 20. J Mol Biol. 2014. PMID: 24657767 Free article.
Assays for histone deacetylases.
Hauser AT, Jung M, Jung M. Hauser AT, et al. Curr Top Med Chem. 2009;9(3):227-34. doi: 10.2174/156802609788085269. Curr Top Med Chem. 2009. PMID: 19355987 Review.
Carbamate prodrug concept for hydroxamate HDAC inhibitors.
Schlimme S, Hauser AT, Carafa V, Heinke R, Kannan S, Stolfa DA, Cellamare S, Carotti A, Altucci L, Jung M, Sippl W. Schlimme S, et al. Among authors: hauser at. ChemMedChem. 2011 Jul 4;6(7):1193-8. doi: 10.1002/cmdc.201100007. Epub 2011 Mar 17. ChemMedChem. 2011. PMID: 21416613 No abstract available.
Chemical probes: sharpen your epigenetic tools.
Hauser AT, Jung M. Hauser AT, et al. Nat Chem Biol. 2011 Jul 18;7(8):499-500. doi: 10.1038/nchembio.615. Nat Chem Biol. 2011. PMID: 21769094 No abstract available.
24 results