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CinA mediates multidrug tolerance in Mycobacterium tuberculosis.
Kreutzfeldt KM, Jansen RS, Hartman TE, Gouzy A, Wang R, Krieger IV, Zimmerman MD, Gengenbacher M, Sarathy JP, Xie M, Dartois V, Sacchettini JC, Rhee KY, Schnappinger D, Ehrt S. Kreutzfeldt KM, et al. Among authors: hartman te. Nat Commun. 2022 Apr 22;13(1):2203. doi: 10.1038/s41467-022-29832-1. Nat Commun. 2022. PMID: 35459278 Free PMC article.
φ(2)GFP10, a high-intensity fluorophage, enables detection and rapid drug susceptibility testing of Mycobacterium tuberculosis directly from sputum samples.
Jain P, Hartman TE, Eisenberg N, O'Donnell MR, Kriakov J, Govender K, Makume M, Thaler DS, Hatfull GF, Sturm AW, Larsen MH, Moodley P, Jacobs WR Jr. Jain P, et al. Among authors: hartman te. J Clin Microbiol. 2012 Apr;50(4):1362-9. doi: 10.1128/JCM.06192-11. Epub 2012 Jan 25. J Clin Microbiol. 2012. PMID: 22278833 Free PMC article.
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
Park Y, Pacitto A, Bayliss T, Cleghorn LA, Wang Z, Hartman T, Arora K, Ioerger TR, Sacchettini J, Rizzi M, Donini S, Blundell TL, Ascher DB, Rhee K, Breda A, Zhou N, Dartois V, Jonnala SR, Via LE, Mizrahi V, Epemolu O, Stojanovski L, Simeons F, Osuna-Cabello M, Ellis L, MacKenzie CJ, Smith AR, Davis SH, Murugesan D, Buchanan KI, Turner PA, Huggett M, Zuccotto F, Rebollo-Lopez MJ, Lafuente-Monasterio MJ, Sanz O, Diaz GS, Lelièvre J, Ballell L, Selenski C, Axtman M, Ghidelli-Disse S, Pflaumer H, Bösche M, Drewes G, Freiberg GM, Kurnick MD, Srikumaran M, Kempf DJ, Green SR, Ray PC, Read K, Wyatt P, Barry CE 3rd, Boshoff HI. Park Y, et al. ACS Infect Dis. 2017 Jan 13;3(1):18-33. doi: 10.1021/acsinfecdis.6b00103. Epub 2016 Oct 17. ACS Infect Dis. 2017. PMID: 27704782 Free PMC article.
Metabolic Perspectives on Persistence.
Hartman TE, Wang Z, Jansen RS, Gardete S, Rhee KY. Hartman TE, et al. Microbiol Spectr. 2017 Jan;5(1):10.1128/microbiolspec.TBTB2-0026-2016. doi: 10.1128/microbiolspec.TBTB2-0026-2016. Microbiol Spectr. 2017. PMID: 28155811 Free PMC article. Review.
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition.
Ballinger E, Mosior J, Hartman T, Burns-Huang K, Gold B, Morris R, Goullieux L, Blanc I, Vaubourgeix J, Lagrange S, Fraisse L, Sans S, Couturier C, Bacqué E, Rhee K, Scarry SM, Aubé J, Yang G, Ouerfelli O, Schnappinger D, Ioerger TR, Engelhart CA, McConnell JA, McAulay K, Fay A, Roubert C, Sacchettini J, Nathan C. Ballinger E, et al. Science. 2019 Feb 1;363(6426):eaau8959. doi: 10.1126/science.aau8959. Science. 2019. PMID: 30705156 Free PMC article.
128 results