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SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD - Possible Implications for Interstitial Fibrosis.
Brake SJ, Eapen MS, McAlinden KD, Markos J, Haug G, Larby J, Chia C, Hardikar A, Singhera GK, Hackett TL, Lu W, Sohal SS. Brake SJ, et al. Among authors: hardikar a. Int J Chron Obstruct Pulmon Dis. 2022 Jan 11;17:101-115. doi: 10.2147/COPD.S329783. eCollection 2022. Int J Chron Obstruct Pulmon Dis. 2022. PMID: 35046647 Free PMC article.
Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.
Eapen MS, Hansbro PM, Larsson-Callerfelt AK, Jolly MK, Myers S, Sharma P, Jones B, Rahman MA, Markos J, Chia C, Larby J, Haug G, Hardikar A, Weber HC, Mabeza G, Cavalheri V, Khor YH, McDonald CF, Sohal SS. Eapen MS, et al. Among authors: hardikar a. Drugs. 2018 Nov;78(16):1717-1740. doi: 10.1007/s40265-018-1001-8. Drugs. 2018. PMID: 30392114 Review.
Dysregulation of endocytic machinery and ACE2 in small airways of smokers and COPD patients can augment their susceptibility to SARS-CoV-2 (COVID-19) infections.
Eapen MS, Lu W, Hackett TL, Singhera GK, Thompson IE, McAlinden KD, Hardikar A, Weber HC, Haug G, Wark PAB, Chia C, Sohal SS. Eapen MS, et al. Among authors: hardikar a. Am J Physiol Lung Cell Mol Physiol. 2021 Jan 1;320(1):L158-L163. doi: 10.1152/ajplung.00437.2020. Epub 2020 Nov 11. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33174446 Free PMC article.
Increased myofibroblasts in the small airways, and relationship to remodelling and functional changes in smokers and COPD patients: potential role of epithelial-mesenchymal transition.
Eapen MS, Lu W, Hackett TL, Singhera GK, Mahmood MQ, Hardikar A, Ward C, Walters EH, Sohal SS. Eapen MS, et al. Among authors: hardikar a. ERJ Open Res. 2021 Jun 7;7(2):00876-2020. doi: 10.1183/23120541.00876-2020. eCollection 2021 Apr. ERJ Open Res. 2021. PMID: 34109247 Free PMC article.
Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension.
Bhattarai P, Lu W, Gaikwad AV, Dey S, Chia C, Larby J, Haug G, Hardikar A, Williams A, Kaur Singhera G, Hackett TL, Eapen MS, Sohal SS. Bhattarai P, et al. Among authors: hardikar a. ERJ Open Res. 2022 Dec 5;8(4):00254-2022. doi: 10.1183/23120541.00254-2022. eCollection 2022 Oct. ERJ Open Res. 2022. PMID: 36478915 Free PMC article.
Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition.
Brake SJ, Lu W, Chia C, Haug G, Larby J, Hardikar A, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Brake SJ, et al. Among authors: hardikar a. Front Immunol. 2023 Jun 26;14:1216506. doi: 10.3389/fimmu.2023.1216506. eCollection 2023. Front Immunol. 2023. PMID: 37435075 Free PMC article.
Endothelial to mesenchymal transition is an active process in smokers and patients with early COPD contributing to pulmonary arterial pathology.
Bhattarai P, Lu W, Hardikar A, Dey S, Gaikwad AV, Shahzad AM, Chia C, Williams A, Singhera GK, Hackett TL, Eapen MS, Sohal SS. Bhattarai P, et al. Among authors: hardikar a. ERJ Open Res. 2024 Feb 12;10(1):00767-2023. doi: 10.1183/23120541.00767-2023. eCollection 2024 Jan. ERJ Open Res. 2024. PMID: 38348240 Free PMC article.
154 results