Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary fibrosis and vascular obliteration?

Eur Respir J. 2020 Oct 15;56(4):2003167. doi: 10.1183/13993003.03167-2020. Print 2020 Oct.

Authors

Mathew Suji Eapen¹, Wenying Lu¹, Archana Vijay Gaikwad¹, Prem Bhattarai¹, Collin Chia^{1

2}, Ashutosh Hardikar^{1

3}, Greg Haug^{1

2}, Sukhwinder Singh Sohal¹

Affiliations

¹ Respiratory Translational Research Group, Department of Laboratory Medicine, School of Health Sciences, College of Health and Medicine, University of Tasmania, Launceston, Australia.
² Department of Respiratory Medicine, Launceston General Hospital, Launceston, Australia.
³ Department of Cardiothoracic Surgery, Royal Hobart Hospital, Hobart, Australia.

Abstract

Endothelial to mesenchymal transition (EndMT) could lead to post-COVID-19 pulmonary fibrosis and vascular remodelling https://bit.ly/2QqSKxT

Publication types

Letter
Comment

MeSH terms

Betacoronavirus
COVID-19
Coronavirus Infections*
Endothelial Cells
Epithelial-Mesenchymal Transition
Humans
Infections*
Pandemics*
Pneumonia, Viral*
Pulmonary Fibrosis*
SARS-CoV-2
Severe acute respiratory syndrome-related coronavirus*