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Page 1
Chemical Synergy between Ionophore PBT2 and Zinc Reverses Antibiotic Resistance.
Bohlmann L, De Oliveira DMP, El-Deeb IM, Brazel EB, Harbison-Price N, Ong CY, Rivera-Hernandez T, Ferguson SA, Cork AJ, Phan MD, Soderholm AT, Davies MR, Nimmo GR, Dougan G, Schembri MA, Cook GM, McEwan AG, von Itzstein M, McDevitt CA, Walker MJ. Bohlmann L, et al. mBio. 2018 Dec 11;9(6):e02391-18. doi: 10.1128/mBio.02391-18. mBio. 2018. PMID: 30538186 Free PMC article.
Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2.
Harbison-Price N, Ferguson SA, Heikal A, Taiaroa G, Hards K, Nakatani Y, Rennison D, Brimble MA, El-Deeb IM, Bohlmann L, McDevitt CA, von Itzstein M, Walker MJ, Cook GM. Harbison-Price N, et al. mSphere. 2020 Mar 18;5(2):e00157-20. doi: 10.1128/mSphere.00157-20. mSphere. 2020. PMID: 32188750 Free PMC article.
Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds.
McGowan JE, Harper AD, Davison EK, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, Rennison D. McGowan JE, et al. Among authors: harbison price n. Bioorg Med Chem Lett. 2020 Jun 1;30(11):127110. doi: 10.1016/j.bmcl.2020.127110. Epub 2020 Mar 16. Bioorg Med Chem Lett. 2020. PMID: 32229060
C-2 derivatized 8-sulfonamidoquinolines as antibacterial compounds.
Davison EK, McGowan JE, Li FF, Harper AD, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, Rennison D. Davison EK, et al. Among authors: harbison price n. Bioorg Med Chem. 2021 Jan 1;29:115837. doi: 10.1016/j.bmc.2020.115837. Epub 2020 Nov 6. Bioorg Med Chem. 2021. PMID: 33223463
Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection.
De Oliveira DMP, Forde BM, Phan MD, Steiner B, Zhang B, Zuegg J, El-Deeb IM, Li G, Keller N, Brouwer S, Harbison-Price N, Cork AJ, Bauer MJ, Alquethamy SF, Beatson SA, Roberts JA, Paterson DL, McEwan AG, Blaskovich MAT, Schembri MA, McDevitt CA, von Itzstein M, Walker MJ. De Oliveira DMP, et al. Among authors: harbison price n. mBio. 2022 Feb 22;13(1):e0351721. doi: 10.1128/mbio.03517-21. Epub 2022 Jan 11. mBio. 2022. PMID: 35012353 Free PMC article.
Neurodegenerative Disease Treatment Drug PBT2 Breaks Intrinsic Polymyxin Resistance in Gram-Positive Bacteria.
De Oliveira DMP, Keller B, Hayes AJ, Ong CY, Harbison-Price N, El-Deeb IM, Li G, Keller N, Bohlmann L, Brouwer S, Turner AG, Cork AJ, Jones TR, Paterson DL, McEwan AG, Davies MR, McDevitt CA, Itzstein MV, Walker MJ. De Oliveira DMP, et al. Among authors: harbison price n. Antibiotics (Basel). 2022 Mar 25;11(4):449. doi: 10.3390/antibiotics11040449. Antibiotics (Basel). 2022. PMID: 35453201 Free PMC article.
Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA.
Davies MR, Keller N, Brouwer S, Jespersen MG, Cork AJ, Hayes AJ, Pitt ME, De Oliveira DMP, Harbison-Price N, Bertolla OM, Mediati DG, Curren BF, Taiaroa G, Lacey JA, Smith HV, Fang NX, Coin LJM, Stevens K, Tong SYC, Sanderson-Smith M, Tree JJ, Irwin AD, Grimwood K, Howden BP, Jennison AV, Walker MJ. Davies MR, et al. Among authors: harbison price n. Nat Commun. 2023 Feb 24;14(1):1051. doi: 10.1038/s41467-023-36717-4. Nat Commun. 2023. PMID: 36828918 Free PMC article.
Pathogenesis, epidemiology and control of Group A Streptococcus infection.
Brouwer S, Rivera-Hernandez T, Curren BF, Harbison-Price N, De Oliveira DMP, Jespersen MG, Davies MR, Walker MJ. Brouwer S, et al. Among authors: harbison price n. Nat Rev Microbiol. 2023 Jul;21(7):431-447. doi: 10.1038/s41579-023-00865-7. Epub 2023 Mar 9. Nat Rev Microbiol. 2023. PMID: 36894668 Free PMC article. Review.
Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.
Mu A, Klare WP, Baines SL, Ignatius Pang CN, Guérillot R, Harbison-Price N, Keller N, Wilksch J, Nhu NTK, Phan MD, Keller B, Nijagal B, Tull D, Dayalan S, Chua HHC, Skoneczny D, Koval J, Hachani A, Shah AD, Neha N, Jadhav S, Partridge SR, Cork AJ, Peters K, Bertolla O, Brouwer S, Hancock SJ, Álvarez-Fraga L, De Oliveira DMP, Forde B, Dale A, Mujchariyakul W, Walsh CJ, Monk I, Fitzgerald A, Lum M, Correa-Ospina C, Roy Chowdhury P, Parton RG, De Voss J, Beckett J, Monty F, McKinnon J, Song X, Stephen JR, Everest M, Bellgard MI, Tinning M, Leeming M, Hocking D, Jebeli L, Wang N, Ben Zakour N, Yasar SA, Vecchiarelli S, Russell T, Zaw T, Chen T, Teng D, Kassir Z, Lithgow T, Jenney A, Cole JN, Nizet V, Sorrell TC, Peleg AY, Paterson DL, Beatson SA, Wu J, Molloy MP, Syme AE, Goode RJA, Hunter AA, Bowland G, West NP, Wilkins MR, Djordjevic SP, Davies MR, Seemann T, Howden BP, Pascovici D, Tyagi S, Schittenhelm RB, De Souza DP, McConville MJ, Iredell JR, Cordwell SJ, Strugnell RA, Stinear TP, Schembri MA, Walker MJ. Mu A, et al. Among authors: harbison price n. Nat Commun. 2023 Mar 18;14(1):1530. doi: 10.1038/s41467-023-37200-w. Nat Commun. 2023. PMID: 36934086 Free PMC article.
12 results