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Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera.
Tong Y, Zhang P, Yang X, Liu X, Zhang J, Grudniewska M, Jung I, Abegg D, Liu J, Childs-Disney JL, Gibaut QMR, Haniff HS, Adibekian A, Mouradian MM, Disney MD. Tong Y, et al. Among authors: haniff hs. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306682120. doi: 10.1073/pnas.2306682120. Epub 2024 Jan 5. Proc Natl Acad Sci U S A. 2024. PMID: 38181056
Programming inactive RNA-binding small molecules into bioactive degraders.
Tong Y, Lee Y, Liu X, Childs-Disney JL, Suresh BM, Benhamou RI, Yang C, Li W, Costales MG, Haniff HS, Sievers S, Abegg D, Wegner T, Paulisch TO, Lekah E, Grefe M, Crynen G, Van Meter M, Wang T, Gibaut QMR, Cleveland JL, Adibekian A, Glorius F, Waldmann H, Disney MD. Tong Y, et al. Among authors: haniff hs. Nature. 2023 Jun;618(7963):169-179. doi: 10.1038/s41586-023-06091-8. Epub 2023 May 24. Nature. 2023. PMID: 37225982 Free PMC article.
A map of the SARS-CoV-2 RNA structurome.
Andrews RJ, O'Leary CA, Tompkins VS, Peterson JM, Haniff HS, Williams C, Disney MD, Moss WN. Andrews RJ, et al. Among authors: haniff hs. NAR Genom Bioinform. 2021 May 22;3(2):lqab043. doi: 10.1093/nargab/lqab043. eCollection 2021 Jun. NAR Genom Bioinform. 2021. PMID: 34046592 Free PMC article.
An in silico map of the SARS-CoV-2 RNA Structurome.
Andrews RJ, Peterson JM, Haniff HS, Chen J, Williams C, Grefe M, Disney MD, Moss WN. Andrews RJ, et al. Among authors: haniff hs. bioRxiv [Preprint]. 2020 Apr 18:2020.04.17.045161. doi: 10.1101/2020.04.17.045161. bioRxiv. 2020. PMID: 32511381 Free PMC article. Updated. Preprint.
17 results