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Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration.
Ryan SK, Zelic M, Han Y, Teeple E, Chen L, Sadeghi M, Shankara S, Guo L, Li C, Pontarelli F, Jensen EH, Comer AL, Kumar D, Zhang M, Gans J, Zhang B, Proto JD, Saleh J, Dodge JC, Savova V, Rajpal D, Ofengeim D, Hammond TR. Ryan SK, et al. Among authors: hammond tr. Nat Neurosci. 2023 Jan;26(1):12-26. doi: 10.1038/s41593-022-01221-3. Epub 2022 Dec 19. Nat Neurosci. 2023. PMID: 36536241 Free PMC article.
Therapeutic inhibition of ferroptosis in neurodegenerative disease.
Ryan SK, Ugalde CL, Rolland AS, Skidmore J, Devos D, Hammond TR. Ryan SK, et al. Among authors: hammond tr. Trends Pharmacol Sci. 2023 Oct;44(10):674-688. doi: 10.1016/j.tips.2023.07.007. Epub 2023 Aug 30. Trends Pharmacol Sci. 2023. PMID: 37657967 Review.
Plaque attack by microglial PLCγ2.
Comer AL, Hammond TR. Comer AL, et al. Among authors: hammond tr. Immunity. 2023 Sep 12;56(9):1985-1987. doi: 10.1016/j.immuni.2023.08.012. Immunity. 2023. PMID: 37703828
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.
Marsh SE, Walker AJ, Kamath T, Dissing-Olesen L, Hammond TR, de Soysa TY, Young AMH, Murphy S, Abdulraouf A, Nadaf N, Dufort C, Walker AC, Lucca LE, Kozareva V, Vanderburg C, Hong S, Bulstrode H, Hutchinson PJ, Gaffney DJ, Hafler DA, Franklin RJM, Macosko EZ, Stevens B. Marsh SE, et al. Among authors: hammond tr. Nat Neurosci. 2022 Mar;25(3):306-316. doi: 10.1038/s41593-022-01022-8. Epub 2022 Mar 8. Nat Neurosci. 2022. PMID: 35260865
Author Correction: Schizophrenia risk from complex variation of complement component 4.
Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Daly MJ, Carroll MC, Stevens B, McCarroll SA. Sekar A, et al. Among authors: hammond tr. Nature. 2022 Jan;601(7892):E4-E5. doi: 10.1038/s41586-021-04202-x. Nature. 2022. PMID: 34912127 No abstract available.
A map of transcriptional heterogeneity and regulatory variation in human microglia.
Young AMH, Kumasaka N, Calvert F, Hammond TR, Knights A, Panousis N, Park JS, Schwartzentruber J, Liu J, Kundu K, Segel M, Murphy NA, McMurran CE, Bulstrode H, Correia J, Budohoski KP, Joannides A, Guilfoyle MR, Trivedi R, Kirollos R, Morris R, Garnett MR, Timofeev I, Jalloh I, Holland K, Mannion R, Mair R, Watts C, Price SJ, Kirkpatrick PJ, Santarius T, Mountjoy E, Ghoussaini M, Soranzo N, Bayraktar OA, Stevens B, Hutchinson PJ, Franklin RJM, Gaffney DJ. Young AMH, et al. Among authors: hammond tr. Nat Genet. 2021 Jun;53(6):861-868. doi: 10.1038/s41588-021-00875-2. Epub 2021 Jun 3. Nat Genet. 2021. PMID: 34083789 Free PMC article.
Immune Signaling in Neurodegeneration.
Hammond TR, Marsh SE, Stevens B. Hammond TR, et al. Immunity. 2019 Apr 16;50(4):955-974. doi: 10.1016/j.immuni.2019.03.016. Immunity. 2019. PMID: 30995509 Free PMC article. Review.
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Marsh SE, Saunders A, Macosko E, Ginhoux F, Chen J, Franklin RJM, Piao X, McCarroll SA, Stevens B. Hammond TR, et al. Immunity. 2019 Jan 15;50(1):253-271.e6. doi: 10.1016/j.immuni.2018.11.004. Epub 2018 Nov 21. Immunity. 2019. PMID: 30471926 Free PMC article.
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