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Using multiple real-world dermoscopic photographs of one lesion improves melanoma classification via deep learning.
Hekler A, Maron RC, Haggenmüller S, Schmitt M, Wies C, Utikal JS, Meier F, Hobelsberger S, Gellrich FF, Sergon M, Hauschild A, French LE, Heinzerling L, Schlager JG, Ghoreschi K, Schlaak M, Hilke FJ, Poch G, Korsing S, Berking C, Heppt MV, Erdmann M, Haferkamp S, Drexler K, Schadendorf D, Sondermann W, Goebeler M, Schilling B, Kather JN, Krieghoff-Henning E, Brinker TJ. Hekler A, et al. Among authors: haferkamp s. J Am Acad Dermatol. 2024 May;90(5):1028-1031. doi: 10.1016/j.jaad.2023.11.065. Epub 2024 Jan 8. J Am Acad Dermatol. 2024. PMID: 38199280 Free article. No abstract available.
Adjuvant immunotherapy with nivolumab versus observation in completely resected Merkel cell carcinoma (ADMEC-O): disease-free survival results from a randomised, open-label, phase 2 trial.
Becker JC, Ugurel S, Leiter U, Meier F, Gutzmer R, Haferkamp S, Zimmer L, Livingstone E, Eigentler TK, Hauschild A, Kiecker F, Hassel JC, Mohr P, Fluck M, Thomas I, Garzarolli M, Grimmelmann I, Drexler K, Spillner AN, Eckhardt S, Schadendorf D; DeCOG. Becker JC, et al. Among authors: haferkamp s. Lancet. 2023 Sep 2;402(10404):798-808. doi: 10.1016/S0140-6736(23)00769-9. Epub 2023 Jul 11. Lancet. 2023. PMID: 37451295 Clinical Trial.
Dermatologist-like explainable AI enhances trust and confidence in diagnosing melanoma.
Chanda T, Hauser K, Hobelsberger S, Bucher TC, Garcia CN, Wies C, Kittler H, Tschandl P, Navarrete-Dechent C, Podlipnik S, Chousakos E, Crnaric I, Majstorovic J, Alhajwan L, Foreman T, Peternel S, Sarap S, Özdemir İ, Barnhill RL, Llamas-Velasco M, Poch G, Korsing S, Sondermann W, Gellrich FF, Heppt MV, Erdmann M, Haferkamp S, Drexler K, Goebeler M, Schilling B, Utikal JS, Ghoreschi K, Fröhling S, Krieghoff-Henning E; Reader Study Consortium; Brinker TJ. Chanda T, et al. Among authors: haferkamp s. Nat Commun. 2024 Jan 15;15(1):524. doi: 10.1038/s41467-023-43095-4. Nat Commun. 2024. PMID: 38225244 Free PMC article.
Genetic alterations driving metastatic colony formation are acquired outside of the primary tumour in melanoma.
Werner-Klein M, Scheitler S, Hoffmann M, Hodak I, Dietz K, Lehnert P, Naimer V, Polzer B, Treitschke S, Werno C, Markiewicz A, Weidele K, Czyz Z, Hohenleutner U, Hafner C, Haferkamp S, Berneburg M, Rümmele P, Ulmer A, Klein CA. Werner-Klein M, et al. Among authors: haferkamp s. Nat Commun. 2018 Feb 9;9(1):595. doi: 10.1038/s41467-017-02674-y. Nat Commun. 2018. PMID: 29426936 Free PMC article.
Single cell polarity in liquid phase facilitates tumour metastasis.
Lorentzen A, Becker PF, Kosla J, Saini M, Weidele K, Ronchi P, Klein C, Wolf MJ, Geist F, Seubert B, Ringelhan M, Mihic-Probst D, Esser K, Roblek M, Kuehne F, Bianco G, O'Connor T, Müller Q, Schuck K, Lange S, Hartmann D, Spaich S, Groß O, Utikal J, Haferkamp S, Sprick MR, Damle-Vartak A, Hapfelmeier A, Hüser N, Protzer U, Trumpp A, Saur D, Vartak N, Klein CA, Polzer B, Borsig L, Heikenwalder M. Lorentzen A, et al. Among authors: haferkamp s. Nat Commun. 2018 Feb 28;9(1):887. doi: 10.1038/s41467-018-03139-6. Nat Commun. 2018. PMID: 29491397 Free PMC article.
Cancer-associated cells release citrate to support tumour metastatic progression.
Drexler K, Schmidt KM, Jordan K, Federlin M, Milenkovic VM, Liebisch G, Artati A, Schmidl C, Madej G, Tokarz J, Cecil A, Jagla W, Haerteis S, Aung T, Wagner C, Kolodziejczyk M, Heinke S, Stanton EH, Schwertner B, Riegel D, Wetzel CH, Buchalla W, Proescholdt M, Klein CA, Berneburg M, Schlitt HJ, Brabletz T, Ziegler C, Parkinson EK, Gaumann A, Geissler EK, Adamski J, Haferkamp S, Mycielska ME. Drexler K, et al. Among authors: haferkamp s. Life Sci Alliance. 2021 Mar 23;4(6):e202000903. doi: 10.26508/lsa.202000903. Print 2021 Jun. Life Sci Alliance. 2021. PMID: 33758075 Free PMC article.
153 results