Using multiple real-world dermoscopic photographs of one lesion improves melanoma classification via deep learning

Achim Hekler; Roman C Maron; Sarah Haggenmüller; Max Schmitt; Christoph Wies; Jochen S Utikal; Friedegund Meier; Sarah Hobelsberger; Frank F Gellrich; Mildred Sergon; Axel Hauschild; Lars E French; Lucie Heinzerling; Justin G Schlager; Kamran Ghoreschi; Max Schlaak; Franz J Hilke; Gabriela Poch; Sören Korsing; Carola Berking; Markus V Heppt; Michael Erdmann; Sebastian Haferkamp; Konstantin Drexler; Dirk Schadendorf; Wiebke Sondermann; Matthias Goebeler; Bastian Schilling; Jakob N Kather; Eva Krieghoff-Henning; Titus J Brinker

doi:10.1016/j.jaad.2023.11.065

Using multiple real-world dermoscopic photographs of one lesion improves melanoma classification via deep learning

J Am Acad Dermatol. 2024 May;90(5):1028-1031. doi: 10.1016/j.jaad.2023.11.065. Epub 2024 Jan 8.

Authors

Achim Hekler¹, Roman C Maron¹, Sarah Haggenmüller¹, Max Schmitt¹, Christoph Wies², Jochen S Utikal³, Friedegund Meier⁴, Sarah Hobelsberger⁴, Frank F Gellrich⁴, Mildred Sergon⁴, Axel Hauschild⁵, Lars E French⁶, Lucie Heinzerling⁷, Justin G Schlager⁸, Kamran Ghoreschi⁹, Max Schlaak⁹, Franz J Hilke⁹, Gabriela Poch⁹, Sören Korsing⁹, Carola Berking¹⁰, Markus V Heppt¹⁰, Michael Erdmann¹⁰, Sebastian Haferkamp¹¹, Konstantin Drexler¹¹, Dirk Schadendorf¹², Wiebke Sondermann¹², Matthias Goebeler¹³, Bastian Schilling¹³, Jakob N Kather¹⁴, Eva Krieghoff-Henning¹, Titus J Brinker¹⁵

Affiliations

¹ Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
² Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany; Medical Faculty, University Heidelberg, Heidelberg, Germany.
³ Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany; Skin Cancer Unit, German Cancer Research Center (DKFZ), Heidelberg, Germany; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.
⁴ Department of Dermatology, Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
⁵ Department of Dermatology, University Hospital (UKSH), Kiel, Germany.
⁶ Department of Dermatology and Allergy, University Hospital, LMU Munich, Munich, Germany; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, Miami, Florida.
⁷ Department of Dermatology and Allergy, University Hospital, LMU Munich, Munich, Germany; Department of Dermatology, University Hospital Erlangen, Comprehensive Cancer Center Erlangen - European Metropolitan Region Nürnberg, CCC Alliance WERA, Erlangen, Germany.
⁸ Department of Dermatology and Allergy, University Hospital, LMU Munich, Munich, Germany.
⁹ Department of Dermatology, Venereology and Allergology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
¹⁰ Department of Dermatology, University Hospital Erlangen, Comprehensive Cancer Center Erlangen - European Metropolitan Region Nürnberg, CCC Alliance WERA, Erlangen, Germany.
¹¹ Department of Dermatology, University Hospital Regensburg, Regensburg, Germany.
¹² Department of Dermatology, Venereology and Allergology, University Hospital Essen, Essen, Germany.
¹³ Department of Dermatology, Venereology and Allergology, University Hospital Würzburg and National Center for Tumor Diseases (NCT) WERA Würzburg, Würzburg, Germany.
¹⁴ Else Kroener Fresenius Center for Digital Health, Technical University Dresden, Dresden, Germany.
¹⁵ Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: titus.brinker@dkfz.de.

PMID: 38199280
DOI: 10.1016/j.jaad.2023.11.065

No abstract available

Keywords: artificial intelligence; deep learning; dermatology; dermoscopy; diagnosis; diagnostic accuracy; melanoma; robustness; uncertainty estimation.

MeSH terms

Algorithms
Deep Learning*
Dermoscopy
Humans
Melanoma* / diagnostic imaging
Melanoma* / pathology
Skin Neoplasms* / diagnostic imaging
Skin Neoplasms* / pathology