Guthridge M - Search Results

1

Molecular basis of cytokine receptor activation.

Lopez AF, Hercus TR, Ekert P, Littler DR, Guthridge M, Thomas D, Ramshaw HS, Stomski F, Perugini M, D'Andrea R, Grimbaldeston M, Parker MW. Lopez AF, et al. Among authors: guthridge m. IUBMB Life. 2010 Jul;62(7):509-18. doi: 10.1002/iub.350. IUBMB Life. 2010. PMID: 20540154 Free article. Review.

2

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.

Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, Powell J, Ramshaw H, Woodcock JM, Xu Y, Guthridge M, McKinstry WJ, Lopez AF, Parker MW. Hansen G, et al. Among authors: guthridge m. Cell. 2008 Aug 8;134(3):496-507. doi: 10.1016/j.cell.2008.05.053. Cell. 2008. PMID: 18692472 Free article.

3

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.

Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, Parker MW, Lopez AF. Hercus TR, et al. Blood. 2009 Aug 13;114(7):1289-98. doi: 10.1182/blood-2008-12-164004. Epub 2009 May 12. Blood. 2009. PMID: 19436055 Free PMC article. Review.

4

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors.

Guthridge MA, Stomski FC, Thomas D, Woodcock JM, Bagley CJ, Berndt MC, Lopez AF. Guthridge MA, et al. Stem Cells. 1998;16(5):301-13. doi: 10.1002/stem.160301. Stem Cells. 1998. PMID: 9766809 Review.

5

Structural and functional hot spots in cytokine receptors.

Bagley CJ, Woodcock JM, Guthridge MA, Stomski FC, Lopez AF. Bagley CJ, et al. Among authors: guthridge ma. Int J Hematol. 2001 Apr;73(3):299-307. doi: 10.1007/BF02981954. Int J Hematol. 2001. PMID: 11345195 Review.

6

Phosphotyrosine/phosphoserine binary switches: a new paradigm for the regulation of PI3K signalling and growth factor pleiotropy?

Guthridge MA, Lopez AF. Guthridge MA, et al. Biochem Soc Trans. 2007 Apr;35(Pt 2):250-2. doi: 10.1042/BST0350250. Biochem Soc Trans. 2007. PMID: 17371251

7

14-3-3 protein signaling in development and growth factor responses.

Thomas D, Guthridge M, Woodcock J, Lopez A. Thomas D, et al. Among authors: guthridge m. Curr Top Dev Biol. 2005;67:285-303. doi: 10.1016/S0070-2153(05)67009-3. Curr Top Dev Biol. 2005. PMID: 15949538 Review.

8

The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2.

Guthridge MA, Barry EF, Felquer FA, McClure BJ, Stomski FC, Ramshaw H, Lopez AF. Guthridge MA, et al. Blood. 2004 Feb 1;103(3):820-7. doi: 10.1182/blood-2003-06-1999. Epub 2003 Aug 14. Blood. 2004. PMID: 12920017 Free article.

9

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.

Guthridge MA, Powell JA, Barry EF, Stomski FC, McClure BJ, Ramshaw H, Felquer FA, Dottore M, Thomas DT, To B, Begley CG, Lopez AF. Guthridge MA, et al. EMBO J. 2006 Feb 8;25(3):479-89. doi: 10.1038/sj.emboj.7600948. Epub 2006 Jan 26. EMBO J. 2006. PMID: 16437163 Free PMC article.

10

The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis.

Ramshaw HS, Guthridge MA, Stomski FC, Barry EF, Ooms L, Mitchell CA, Begley CG, Lopez AF. Ramshaw HS, et al. Blood. 2007 Nov 15;110(10):3582-90. doi: 10.1182/blood-2007-01-070391. Epub 2007 Jul 16. Blood. 2007. PMID: 17638849 Free PMC article.

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