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Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA. Guo CJ, et al. Cell. 2017 Jan 26;168(3):517-526.e18. doi: 10.1016/j.cell.2016.12.021. Epub 2017 Jan 19. Cell. 2017. PMID: 28111075 Free PMC article.
Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential.
Skye SM, Zhu W, Romano KA, Guo CJ, Wang Z, Jia X, Kirsop J, Haag B, Lang JM, DiDonato JA, Tang WHW, Lusis AJ, Rey FE, Fischbach MA, Hazen SL. Skye SM, et al. Among authors: guo cj. Circ Res. 2018 Oct 26;123(10):1164-1176. doi: 10.1161/CIRCRESAHA.118.313142. Circ Res. 2018. PMID: 30359185 Free PMC article. Clinical Trial.
A metabolic pathway for bile acid dehydroxylation by the gut microbiome.
Funabashi M, Grove TL, Wang M, Varma Y, McFadden ME, Brown LC, Guo C, Higginbottom S, Almo SC, Fischbach MA. Funabashi M, et al. Nature. 2020 Jun;582(7813):566-570. doi: 10.1038/s41586-020-2396-4. Epub 2020 Jun 17. Nature. 2020. PMID: 32555455 Free PMC article.
Modulating microbiome metabolites in vivo.
Guo CJ. Guo CJ. Science. 2020 Jul 10;369(6500):153. doi: 10.1126/science.abc5620. Science. 2020. PMID: 32646995 No abstract available.
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells.
Campbell C, McKenney PT, Konstantinovsky D, Isaeva OI, Schizas M, Verter J, Mai C, Jin WB, Guo CJ, Violante S, Ramos RJ, Cross JR, Kadaveru K, Hambor J, Rudensky AY. Campbell C, et al. Among authors: guo cj. Nature. 2020 May;581(7809):475-479. doi: 10.1038/s41586-020-2193-0. Epub 2020 Apr 15. Nature. 2020. PMID: 32461639 Free PMC article.
235 results