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Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats.
Karuppagounder V, Bajpai A, Meng S, Arumugam S, Sreedhar R, Giridharan VV, Guha A, Bhimaraj A, Youker KA, Palaniyandi SS, Karmouty-Quintana H, Kamal F, Spiller KL, Watanabe K, Thandavarayan RA. Karuppagounder V, et al. Among authors: guha a. PLoS One. 2018 Jul 19;13(7):e0200697. doi: 10.1371/journal.pone.0200697. eCollection 2018. PLoS One. 2018. PMID: 30024944 Free PMC article.
Pathophysiology of Acute and Chronic Right Heart Failure.
Thandavarayan RA, Chitturi KR, Guha A. Thandavarayan RA, et al. Among authors: guha a. Cardiol Clin. 2020 May;38(2):149-160. doi: 10.1016/j.ccl.2020.01.009. Epub 2020 Mar 5. Cardiol Clin. 2020. PMID: 32284093 Review.
SARS-CoV-2 Mediated Hyperferritinemia and Cardiac Arrest: Preliminary Insights.
VasanthiDharmalingam P, Karuppagounder V, Watanabe K, Karmouty-Quintana H, Palaniyandi SS, Guha A, Thandavarayan RA. VasanthiDharmalingam P, et al. Among authors: guha a. Drug Discov Today. 2021 May;26(5):1265-1274. doi: 10.1016/j.drudis.2021.01.014. Epub 2021 Jan 23. Drug Discov Today. 2021. PMID: 33493677 Free PMC article. Review.
HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis.
Philip K, Mills TW, Davies J, Chen NY, Karmouty-Quintana H, Luo F, Molina JG, Amione-Guerra J, Sinha N, Guha A, Eltzschig HK, Blackburn MR. Philip K, et al. Among authors: guha a. FASEB J. 2017 Nov;31(11):4745-4758. doi: 10.1096/fj.201700219R. Epub 2017 Jul 12. FASEB J. 2017. PMID: 28701304 Free PMC article.
Although hypoxic conditions are present in IPF, hypoxia's role as a direct modulator of macrophage phenotype and identification of factors that regulate ADORA2B expression on AAMs in IPF is not well understood. ...-Y., Karmouty-Quintana, H., Luo, F., Molina, J. G., Amione- …
Although hypoxic conditions are present in IPF, hypoxia's role as a direct modulator of macrophage phenotype and identification of fa …
Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis.
Collum SD, Chen NY, Hernandez AM, Hanmandlu A, Sweeney H, Mertens TCJ, Weng T, Luo F, Molina JG, Davies J, Horan IP, Morrell NW, Amione-Guerra J, Al-Jabbari O, Youker K, Sun W, Rajadas J, Bollyky PL, Akkanti BH, Jyothula S, Sinha N, Guha A, Karmouty-Quintana H. Collum SD, et al. Among authors: guha a. Br J Pharmacol. 2017 Oct;174(19):3284-3301. doi: 10.1111/bph.13947. Epub 2017 Aug 17. Br J Pharmacol. 2017. PMID: 28688167 Free PMC article.
926 results