3'UTR shortening of profibrotic genes and reversibility of fibrosis in patients with end-stage right ventricular failure

Clin Transl Med. 2022 Sep;12(9):e1017. doi: 10.1002/ctm2.1017.

Authors

Rahul Neupane¹, Katarzyna A Cieslik², Keith Youker¹, Suresh Selvaraj Palaniyandi^{3

4}, Ashrith Guha¹, Rajarajan A Thandavarayan¹

Affiliations

¹ DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas.
² Division of Cardiovascular Sciences, Department of Medicine, Baylor College of Medicine, Houston, Texas.
³ Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan.
⁴ Department of Physiology, Wayne State University, Detroit, Michigan.

No abstract available

Keywords: 4HNE; alternative polyadenylation; fibrosis; right ventricle failure.

Publication types

Letter
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural

MeSH terms

3' Untranslated Regions / genetics
Fibrosis
Humans
Polyadenylation*
RNA, Messenger / genetics

Substances

3' Untranslated Regions
RNA, Messenger

Grants and funding

R01 HL139877/HL/NHLBI NIH HHS/United States