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Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease.
Caballero-Camino FJ, Rivilla I, Herraez E, Briz O, Santos-Laso A, Izquierdo-Sanchez L, Lee-Law PY, Rodrigues PM, Munoz-Garrido P, Jin S, Peixoto E, Richard S, Gradilone SA, Perugorria MJ, Esteller M, Bujanda L, Marin JJG, Banales JM, Cossío FP. Caballero-Camino FJ, et al. Among authors: gradilone sa. Hepatology. 2021 Jan;73(1):186-203. doi: 10.1002/hep.31216. Epub 2020 Sep 22. Hepatology. 2021. PMID: 32145077 Free PMC article.
The primary cilium: Its role as a tumor suppressor organelle.
Peixoto E, Richard S, Pant K, Biswas A, Gradilone SA. Peixoto E, et al. Among authors: gradilone sa. Biochem Pharmacol. 2020 May;175:113906. doi: 10.1016/j.bcp.2020.113906. Epub 2020 Mar 10. Biochem Pharmacol. 2020. PMID: 32169416 Free PMC article. Review.
HDAC6-dependent ciliophagy is involved in ciliary loss and cholangiocarcinoma growth in human cells and murine models.
Peixoto E, Jin S, Thelen K, Biswas A, Richard S, Morleo M, Mansini A, Holtorf S, Carbone F, Pastore N, Ballabio A, Franco B, Gradilone SA. Peixoto E, et al. Among authors: gradilone sa. Am J Physiol Gastrointest Liver Physiol. 2020 Jun 1;318(6):G1022-G1033. doi: 10.1152/ajpgi.00033.2020. Epub 2020 Apr 27. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32338033 Free PMC article.
Histone Deacetylase Sirtuin 1 Promotes Loss of Primary Cilia in Cholangiocarcinoma.
Pant K, Peixoto E, Richard S, Biswas A, O'Sullivan MG, Giama N, Ha Y, Yin J, Carotenuto P, Salati M, Ren Y, Yang R, Franco B, Roberts LR, Gradilone SA. Pant K, et al. Among authors: gradilone sa. Hepatology. 2021 Dec;74(6):3235-3248. doi: 10.1002/hep.32080. Epub 2021 Sep 27. Hepatology. 2021. PMID: 34322899
55 results