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PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.
Wong CW, Evangelou C, Sefton KN, Leshem R, Zhang W, Gopalan V, Chattrakarn S, Fernandez Carro ML, Uzuner E, Mole H, Wilcock DJ, Smith MP, Sergiou K, Telfer BA, Isaac DT, Liu C, Perl NR, Marie K, Lorigan P, Williams KJ, Rao PE, Nagaraju RT, Niepel M, Hurlstone AFL. Wong CW, et al. Among authors: gopalan v. Nat Commun. 2023 Sep 26;14(1):5983. doi: 10.1038/s41467-023-41737-1. Nat Commun. 2023. PMID: 37752135 Free PMC article.
Noncoding RNA circuitry in melanoma onset, plasticity, and therapeutic response.
Grafanaki K, Grammatikakis I, Ghosh A, Gopalan V, Olgun G, Liu H, Kyriakopoulos GC, Skeparnias I, Georgiou S, Stathopoulos C, Hannenhalli S, Merlino G, Marie KL, Day CP. Grafanaki K, et al. Among authors: gopalan v. Pharmacol Ther. 2023 Aug;248:108466. doi: 10.1016/j.pharmthera.2023.108466. Epub 2023 Jun 8. Pharmacol Ther. 2023. PMID: 37301330 Free PMC article. Review.
Melanoma clonal subline analysis uncovers heterogeneity-driven immunotherapy resistance mechanisms.
Gruen C, Yang HH, Sassano A, Wu E, Gopalan V, Marie KL, Castro A, Mehrabadi FR, Wu CH, Church I, Needle GA, Smith C, Chin S, Ebersole J, Marcelus C, Fon A, Liu H, Malikic S, Sahinalp C, Carter H, Hannenhalli S, Day CP, Lee MP, Merlino G, Pérez-Guijarro E. Gruen C, et al. Among authors: gopalan v. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535074. doi: 10.1101/2023.04.03.535074. bioRxiv. 2023. PMID: 37333132 Free PMC article. Preprint.
miRSCAPE - inferring miRNA expression from scRNA-seq data.
Olgun G, Gopalan V, Hannenhalli S. Olgun G, et al. Among authors: gopalan v. iScience. 2022 Aug 17;25(9):104962. doi: 10.1016/j.isci.2022.104962. eCollection 2022 Sep 16. iScience. 2022. PMID: 36060076 Free PMC article.
Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis.
Kaczanowska S, Beury DW, Gopalan V, Tycko AK, Qin H, Clements ME, Drake J, Nwanze C, Murgai M, Rae Z, Ju W, Alexander KA, Kline J, Contreras CF, Wessel KM, Patel S, Hannenhalli S, Kelly MC, Kaplan RN. Kaczanowska S, et al. Among authors: gopalan v. Cell. 2021 Apr 15;184(8):2033-2052.e21. doi: 10.1016/j.cell.2021.02.048. Epub 2021 Mar 24. Cell. 2021. PMID: 33765443 Free PMC article.
423 results